DNA序列中均匀编码和潜在周期性的随机模型。

Stochastic model of homogeneous coding and latent periodicity in DNA sequences.

作者信息

Chaley Maria, Kutyrkin Vladimir

机构信息

Institute of Mathematical Problems of Biology, Russian Academy of Sciences, Institutskaya st., 4, 142290 Pushchino, Russia.

Department of Computational Mathematics and Mathematical Physics, Moscow State Technical University n.a. N.E. Bauman, the 2nd Baumanskaya st., 5, 105005 Moscow, Russia.

出版信息

J Theor Biol. 2016 Feb 7;390:106-16. doi: 10.1016/j.jtbi.2015.11.014. Epub 2015 Nov 30.

DOI:10.1016/j.jtbi.2015.11.014

PMID:26656186

Abstract

The concept of latent triplet periodicity in coding DNA sequences which has been earlier extensively discussed is confirmed in the result of analysis of a number of eukaryotic genomes, where latent periodicity of a new type, called profile periodicity, is recognized in the CDSs. Original model of Stochastic Homogeneous Organization of Coding (SHOC-model) in textual string is proposed. This model explains the existence of latent profile periodicity and regularity in DNA sequences.

摘要

编码DNA序列中潜在三联体周期性的概念，此前已被广泛讨论，在对一些真核生物基因组的分析结果中得到了证实，在这些基因组的编码序列（CDS）中识别出了一种新型的潜在周期性，即轮廓周期性。提出了文本字符串中编码的随机均匀组织的原始模型（SHOC模型）。该模型解释了DNA序列中潜在轮廓周期性和规律性的存在。