McCalmont C, Zanolli M D
Department of Dermatology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina.
Dermatol Clin. 1989 Jul;7(3):591-601.
The rickettsioses have several unifying features. Arthropod vectors are the common means of transmission. Fever, headache, myalgias, and the characteristic eruption (except in Q fever and ehrlichioses) are the hallmarks of the clinical presentation. The diseases share a common pathogenesis, namely, vasculitis, and treatment uniformly consists of tetracycline or chloramphenicol. Distinguishing aspects of these processes include the multitude of different reservoirs, the progression of the rash, and the nonspecific antigen test (Weil-Felix) results.
立克次氏体病有几个共同特征。节肢动物媒介是常见的传播方式。发热、头痛、肌痛以及特征性皮疹(Q热和埃立克体病除外)是临床表现的标志。这些疾病有共同的发病机制,即血管炎,治疗均采用四环素或氯霉素。这些疾病过程的不同之处包括众多不同的储存宿主、皮疹的进展以及非特异性抗原检测(外斐反应)结果。