Kontozoglou T E, Moyana T N
Department of Pathology, St. Joseph's Hospital, London, Ontario, Canada.
Dis Colon Rectum. 1989 Aug;32(8):716-21. doi: 10.1007/BF02555782.
This paper presents two cases of adenosquamous carcinoma of the colon and brings to 39 the total number documented in medical literature. The concurrent glandular and squamous differentiation of the tumor cells was demonstrated by immunocytochemistry and electron microscopy. Evaluation of the biologic characteristics of all the reported cases suggests that malignant squamous elements in colonic carcinomas behave more aggressively than their glandular counterparts. In contradistinction from the pure squamous-cell carcinoma of the colon, adenosquamous carcinoma does not show the same predilection for the right colon.
本文报告了两例结肠腺鳞癌病例,使医学文献中记录的此类病例总数达到39例。通过免疫细胞化学和电子显微镜证实了肿瘤细胞同时存在腺性和鳞状分化。对所有报告病例的生物学特征评估表明,结肠癌中的恶性鳞状成分比腺性成分表现得更具侵袭性。与结肠纯鳞状细胞癌不同,腺鳞癌对右半结肠没有同样的偏好。