输卵管内合子移植作为不明原因不孕症的一种成功治疗方法。

Zygote intrafallopian transfer as a successful treatment for unexplained infertility.

作者信息

Devroey P, Staessen C, Camus M, De Grauwe E, Wisanto A, Van Steirteghem A C

机构信息

Center for Reproductive Medicine, Vrije Universiteit Brussel, Belgium.

出版信息

Fertil Steril. 1989 Aug;52(2):246-9. doi: 10.1016/s0015-0282(16)60850-6.

DOI:10.1016/s0015-0282(16)60850-6

PMID:2666176

Abstract

This study describes the zygote intrafallopian transfer treatment in patients with unexplained infertility. After retrieval, the oocytes were inseminated with 80,000 progressive motile sperm cells per milliliter. If fertilization occurred, a maximum of three zygotes were replaced by laparoscopy in the fimbrial end of one healthy fallopian tube. A pregnancy rate of 48.1% per zygote intrafallopian transfer replacement was obtained. Seventeen pregnancies are actually ongoing, two patients delivered, and seven patients miscarried. Even after replacing a maximum of three zygotes, there were 6 twin and 2 triplet pregnancies.

摘要

本研究描述了不明原因不孕症患者的输卵管内合子移植治疗。取卵后，将卵母细胞与每毫升80000个具有前进运动能力的精子细胞进行受精。如果发生受精，则通过腹腔镜将最多三个合子移植到一条健康输卵管的伞端。每次输卵管内合子移植替换的妊娠率为48.1%。目前实际上有17例妊娠在持续，2例患者分娩，7例患者流产。即使最多移植三个合子，仍有6例双胎妊娠和2例三胎妊娠。