光学相干断层扫描衰减系数定量分析中的学习曲线与观察者间差异

Learning curve and interobserver variance in quantification of the optical coherence tomography attenuation coefficient.

作者信息

Wessels Ronni, de Bruin Daniel M, Faber Dirk J, Sanders Joyce, Vincent Andrew D, van Beurden Marc, van Leeuwen Ton G, Ruers Theo J M

机构信息

Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Department of Surgery, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.

Academic Medical Center-University of Amsterdam, Department of Biomedical Engineering and Physics, Meibergdreef 9, 1105 AZ Amsterdam, The NetherlandscAcademic Medical Center-University of Amsterdam, Department of Urology, Meibergdreef 9, 1105 AZ Amsterdam.

出版信息

J Biomed Opt. 2015;20(12):121313. doi: 10.1117/1.JBO.20.12.121313.

DOI:10.1117/1.JBO.20.12.121313

PMID:26662606

Abstract

The learning curve and interobserver variance of attenuation coefficient (μOCT ) determination from optical coherence tomography (OCT) images were quantified. The μOCT of normal and diseased vulvar tissues was determined at five time points by three novice students and three OCT experts who reached consensus for reference. Students received feedback between time points. Eventually, variance in μOCT was smaller in images of diseased tissue than in images of normal vulvar tissue. The difference between the consensus and student μOCT values was larger for smaller values of μOCT . We conclude that routine μOCT determination for tissue classification does not require extensive training.

摘要

对光学相干断层扫描（OCT）图像中衰减系数（μOCT）测定的学习曲线和观察者间差异进行了量化。三名新手学生和三名OCT专家在五个时间点测定了正常和患病外阴组织的μOCT，并达成了共识作为参考。学生在各时间点之间接受反馈。最终，患病组织图像中μOCT的差异小于正常外阴组织图像。对于较小的μOCT值，共识值与学生μOCT值之间的差异更大。我们得出结论，用于组织分类的常规μOCT测定不需要广泛的培训。