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伊朗儿童从出生到24个月大时的囟门大小。

Fontanel Size from Birth to 24 Months of Age in Iranian Children.

作者信息

Esmaeili Mohammad, Esmaeili Marjan, Ghane Sharbaf Fatemeh, Bokharaie Shirin

机构信息

Pediatrician, Ghaem Medical Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Pediatrician, Iran university of Medical Sciences, Tehran, Iran.

出版信息

Iran J Child Neurol. 2015 Fall;9(4):15-23.

Abstract

OBJECTIVE

Diagnosis of abnormal fontanel size, a potential clue to recognition of different disorders, requires an understanding of the wide variation of normal fontanel size. The anterior fontanel is the largest, prominent and most important for clinical evaluation. The aim of this study was to establish and define normal range of fontanel size from birth to 24 months of age in healthy Iranian children that might be generalized to other populations.

MATERIALS & METHODS: Totally, 550 subjects enrolled randomly in this cross sectional study. They were apparently normal healthy children, from birth to 24 months of age, including 208-term newborn and 342 infant from birth to 2 yr old. Fontanel size was measured and recorded as the mean of the length (anterior- posterior dimension) and width (transverse dimension). Mean anterior fontanel sizes in our samples were classified for periods of 3 months. Nomograms and statistical analyses were performed and depicted by Excel Microsoft Office 2007 and two-tailed t-test respectively.

RESULTS

The mean ±2SD of anterior fontanel size was 2.55±1.92 cm in newborns, 3.37±2.48 (largest size) in 3 months of age. It was closed in all cases in 15-18 months of age. The mean posterior fontanel size was 0.8 cm in newborns and closed in all infants in 2 months of age. There was no significant difference in anterior fontanel size between two genders except in newborn and 6-9 months old (P>0.05).

CONCLUSION

Abnormal fontanel can indicate a serious medical condition. Therefore, it is important to understand normal variations, to utilize standardized techniques for measurement and appropriate standards of normal range in different age groups and populations. This study provides a normal range of mean fontanel size in Iranian infants as a local reference. It might be generalized to other populations.

摘要

目的

囟门大小异常是识别不同疾病的潜在线索,诊断时需要了解正常囟门大小的广泛差异。前囟门最大、最突出,对临床评估最为重要。本研究的目的是确定健康伊朗儿童从出生到24个月大时囟门大小的正常范围,该范围可能适用于其他人群。

材料与方法

本横断面研究共随机纳入550名受试者。他们是出生至24个月大的明显正常健康儿童,包括208名足月儿和342名出生至2岁的婴儿。测量囟门大小并记录为长度(前后径)和宽度(横径)的平均值。我们样本中的平均前囟门大小按3个月的时间段进行分类。分别使用Excel Microsoft Office 2007制作列线图并进行统计分析,采用双尾t检验。

结果

新生儿前囟门大小的平均值±2SD为2.55±1.92厘米,3个月大时为3.37±2.48厘米(最大尺寸)。在15 - 18个月大时所有病例的前囟门均已闭合。新生儿后囟门平均大小为0.8厘米,在2个月大时所有婴儿的后囟门均已闭合。除新生儿和6 - 9个月大的婴儿外,两性之间的前囟门大小无显著差异(P>0.05)。

结论

囟门异常可能表明存在严重的医疗状况。因此,了解正常变异、采用标准化测量技术以及不同年龄组和人群的正常范围适当标准非常重要。本研究提供了伊朗婴儿囟门平均大小的正常范围作为本地参考。它可能适用于其他人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e5/4670973/38e833e626da/ijcn-9-015-g001.jpg

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