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国家子宫内膜癌早期诊断项目第二部分

Project for the National Program of Early Diagnosis of Endometrial Cancer Part II.

作者信息

Bohîlțea R E, Ancăr V, Rădoi V, Furtunescu F, Bohîlțea L C

机构信息

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

J Med Life. 2015 Oct-Dec;8(4):423-31.

Abstract

RATIONALE

Endometrial cancer recorded a peak incidence in ages 60-64 years in Romania. Since 2013, an increased trend of endometrial cancer occurrence has been registered in urban areas as compared with rural ones. Unfortunately, most of the cancer cases are diagnosed too late, in an advanced stage of the disease, resulting into diminished lifetime expectancy. The first part of the article concentrated on issues such as: the description of the study, results, and discussions regarding the study, definitions and terms, risk factors specific for endometrial carcinomas, presentation of the activities of the Program, etc.

OBJECTIVE

Drafting a national program that will serve as an early diagnosis method of endometrial cancer. This second part of the study continues with the presentation of the activities of the Program, analyzes the human resources and materials needed to implement the Program, presents the strategies and the indicators specific for the implementation of the project.

METHODS AND RESULTS

A standardization of the diagnostic steps was proposed and the focus was on 4 key elements for the early diagnosis of endometrial cancer: The first steps were approached in the first part of the study and the second part of the study investigated the proper monitoring of precursor endometrial lesions or cancer associated endometrial lesions and screening high risk populations (Lynch syndrome, Cowden syndrome).

DISCUSSION

Improving medical practice based on diagnostic algorithms and programs improves and increases the lifetime expectancy, due to the fact that endometrial cancer is early diagnosed and treated before it causes serious health problems or even death.

摘要

理论依据

罗马尼亚子宫内膜癌的发病率在60 - 64岁达到峰值。自2013年以来,与农村地区相比,城市地区子宫内膜癌的发病率呈上升趋势。不幸的是,大多数癌症病例在疾病晚期才被诊断出来,导致预期寿命缩短。文章的第一部分集中讨论了以下问题:研究的描述、结果、关于该研究的讨论、定义和术语、子宫内膜癌的特定危险因素、该项目活动的介绍等。

目的

起草一项作为子宫内膜癌早期诊断方法的国家计划。该研究的第二部分继续介绍该项目的活动,分析实施该项目所需的人力资源和物资,介绍实施该项目的具体策略和指标。

方法与结果

提出了诊断步骤的标准化,并将重点放在子宫内膜癌早期诊断的4个关键要素上:第一步在研究的第一部分中进行探讨,研究的第二部分调查对子宫内膜前驱病变或与癌症相关的子宫内膜病变的适当监测以及对高危人群(林奇综合征、考登综合征)的筛查。

讨论

基于诊断算法和项目改进医疗实践可提高预期寿命,因为子宫内膜癌在导致严重健康问题甚至死亡之前就得到了早期诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36b1/4656945/1d38d02b40c4/JMedLife-08-423-g001.jpg

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