Department of Anaesthesia, institut mutualiste Montsouris, 42, boulevard Jourdan, 75674 Paris cedex 14, France.
Department of Anaesthesia, institut mutualiste Montsouris, 42, boulevard Jourdan, 75674 Paris cedex 14, France.
Anaesth Crit Care Pain Med. 2016 Apr;35(2):109-14. doi: 10.1016/j.accpm.2015.08.004. Epub 2015 Dec 5.
Since stroke and myocardial ischaemia are major causes of perioperative morbidity and mortality associated with carotid endarterectomy, monitoring the brain and ensuring the best haemodynamic stability are important goals of the management. As regional anaesthesia was reported to improve haemodynamic stability during carotid endarterectomy (CEA), we conducted a prospective observational study on the efficacy and safety of ultrasound-guided intermediate cervical plexus blocks (CPB), with early (immediate postoperative) and mid-term (day 30) outcomes in awake patients undergoing CEA.
After the ethics committee approval, 50 patients undergoing a carotid endarterectomy with CPB from April 2011 to May 2013 were included. Anaesthesia and surgical dissection parameters, early complications and haemodynamic stability were recorded, as well as neurologic and cardiac outcomes initially and one month later.
Cervical space was easy to locate by ultrasound in 90% of the patients. The quality of anaesthesia and surgical dissection was good in 86 and 88% of patients, respectively. No conversion to GA was required, secondary to a lack of analgesia. Two patients (4%) had severe hypotension (<100mmHg). Three patients required a shunt after carotid clamping for loss of consciousness with a favourable neurological outcome. We observed one elevation of cTnI (0.95ng·ml(-1)) without ECG change and 1 death occurred after a postoperative haemorrhagic stroke.
The present work reports our first 50 cases of intermediate CPB using ultrasound guidance. The results underline that this technique is easy to perform, safe and reliable, provided good surgical conditions with continuous intraoperative neurologic monitoring and stable haemodynamics are respected.
由于中风和心肌缺血是与颈动脉内膜切除术相关的围手术期发病率和死亡率的主要原因,因此监测大脑并确保最佳血液动力学稳定性是管理的重要目标。由于区域麻醉被报道可改善颈动脉内膜切除术(CEA)期间的血液动力学稳定性,我们对清醒患者进行了一项前瞻性观察研究,评估超声引导下中等颈丛阻滞(CPB)的疗效和安全性,以及早期(术后即刻)和中期(第 30 天)结果。
在伦理委员会批准后,纳入了 2011 年 4 月至 2013 年 5 月期间接受 CPB 加颈动脉内膜切除术的 50 例患者。记录麻醉和手术解剖参数、早期并发症和血液动力学稳定性,以及初始和一个月后的神经和心脏结局。
90%的患者通过超声很容易定位颈椎间隙。麻醉和手术解剖质量分别在 86%和 88%的患者中良好。由于缺乏镇痛,无需转为全身麻醉。由于夹闭颈动脉后意识丧失而需要分流的 2 例患者(4%)出现严重低血压(<100mmHg)。3 例患者需要分流,以防止因颈动脉夹闭导致的无意识,神经结局良好。我们观察到 1 例肌钙蛋白 I 升高(0.95ng·ml(-1)),无心电图变化,1 例术后出血性中风死亡。
本研究报告了我们使用超声引导进行的前 50 例中等 CPB 的结果。结果表明,在尊重术中连续神经监测和稳定血液动力学的情况下,该技术易于操作、安全可靠,提供了良好的手术条件。