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超声引导下颈丛神经阻滞联合血管周围局部麻醉在颈动脉内膜剥脱术中的应用:一项随机对照试验

Ultrasound-guided intermediate cervical plexus block and perivascular local anesthetic infiltration for carotid endarterectomy : A randomized controlled trial.

作者信息

Seidel R, Zukowski K, Wree A, Schulze M

机构信息

Department of Anesthesiology and Intensive Care Medicine, HELIOS Medical Center Schwerin, Wismarsche Straße 393-7, 19049, Schwerin, Germany.

Institut of Anatomy, Medical University of Rostock, Rostock, Germany.

出版信息

Anaesthesist. 2016 Dec;65(12):917-924. doi: 10.1007/s00101-016-0230-z. Epub 2016 Oct 14.

Abstract

BACKGROUND AND OBJECTIVE

Ultrasound-guided blocks of the cervical plexus are established anesthetic procedures for carotid endarterectomy. This randomized, double-blind, placebo-controlled study tested the hypothesis that an additional ultrasound-guided periarterial injection of local anesthetic leads to a lower frequency of periarterial supplementation by the surgeon.

METHODS

A total of 40 patients were randomly assigned to 1 of 2 groups. In both groups an ultrasound-guided intermediate cervical plexus block (20 ml of 0.75 % ropivacaine) at the level of the fourth cervical vertebra was performed. In a second step, the needle was inserted from posterolateral to anteromedial (in-plane technique) relative to the internal carotid artery and then, depending on the randomized group assignment, 5 ml of 0.75 % ropivacaine (group 2) or 5 ml of 0.9 % saline (group 1) was injected. The parameters investigated included the need for supplementation, patient comfort, the incidence of side effects and circulatory changes.

RESULTS

The two groups did not significantly differ (p = 0.459) in terms of the need for intraoperative supplementation with 1 % prilocaine with a mean (range) in group 2 of 4.9 ml (0-20 ml), in group 1 of 3.7 ml (0-16 ml) and patient comfort (p = 0.144). In addition, a trend towards a higher complication rate was observed in group 2.

CONCLUSION

For ultrasound-guided intermediate blocks of the cervical plexus, an additional periarterial infiltration showed no advantage. Abandoning this technique leads to a relevant simplification of the blocking technique and tends to reduce block-related side effects.

摘要

背景与目的

超声引导下颈丛阻滞是颈动脉内膜切除术既定的麻醉方法。这项随机、双盲、安慰剂对照研究检验了以下假设:额外进行超声引导下动脉周围局部麻醉药注射会降低外科医生进行动脉周围补充麻醉药的频率。

方法

总共40例患者被随机分为2组中的1组。两组均在第四颈椎水平进行超声引导下颈丛中级阻滞(20毫升0.75%罗哌卡因)。第二步,相对于颈内动脉,将针从后外侧插入至前内侧(平面内技术),然后根据随机分组,注射5毫升0.75%罗哌卡因(第2组)或5毫升0.9%生理盐水(第1组)。所研究的参数包括补充麻醉药的必要性、患者舒适度、副作用发生率及循环变化。

结果

两组在术中补充1%丙胺卡因的必要性方面无显著差异(p = 0.459),第2组的平均值(范围)为4.9毫升(0 - 20毫升),第1组为3.7毫升(0 - 16毫升),且在患者舒适度方面也无显著差异(p = 0.144)。此外,第2组观察到并发症发生率有升高趋势。

结论

对于超声引导下颈丛中级阻滞,额外的动脉周围浸润并无优势。放弃该技术会使阻滞技术显著简化,并倾向于减少与阻滞相关的副作用。

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