Meslin Eric M, Rager Joshua B, Schwartz Peter H, Quaid Kimberly A, Gaffney Margaret M, Duke Jon, Tierney William H
Indiana University Center for Bioethics, 410 West 10th Street, Indianapolis, IN, 46202, USA.
Regenstrief Institute Inc., 410 West 10th Street, Indianapolis, IN, 46202, USA.
Clin Transl Med. 2015 Dec;4(1):36. doi: 10.1186/s40169-015-0077-y. Epub 2015 Dec 14.
Relationships between industry and university-based researchers have been commonplace for decades and have received notable attention concerning the conflicts of interest these relationships may harbor. While new efforts are being made to update conflict of interest policies and make industry relationships with academia more transparent, the development of broader institutional partnerships between industry and academic health centers challenges the efficacy of current policy to effectively manage these innovative partnerships. In this paper, we argue that existing strategies to reduce conflicts of interest are not sufficient to address the emerging models of industry-academic partnerships because they focus too narrowly on financial matters and are not comprehensive enough to mitigate all ethical risk. Moreover, conflict-of-interest strategies are not designed to promote best practices nor the scientific and social benefits of academic-industry collaboration. We propose a framework of principles and benchmarks for "ethically credible partnerships" between industry and academic health centers and describe how this framework may provide a practical and comprehensive approach for designing and evaluating such partnerships.
几十年来,产业界与大学研究人员之间的关系一直很常见,这些关系可能存在的利益冲突也受到了显著关注。虽然人们正在做出新的努力来更新利益冲突政策,并使产业界与学术界的关系更加透明,但产业界与学术健康中心之间更广泛的机构合作伙伴关系的发展,对当前政策有效管理这些创新合作伙伴关系的效力提出了挑战。在本文中,我们认为,现有的减少利益冲突的策略不足以应对新兴的产学研合作伙伴关系模式,因为它们过于狭隘地关注财务问题,不够全面,无法减轻所有的伦理风险。此外,利益冲突策略并非旨在促进最佳实践,也无法推动产学研合作的科学和社会效益。我们提出了一个产业界与学术健康中心之间“符合伦理的可信合作伙伴关系”的原则和基准框架,并描述了该框架如何为设计和评估此类合作伙伴关系提供一种实用且全面的方法。