心脏神经内分泌肿瘤转移：病例报告及文献综述
Cardiac neuroendocrine tumour metastases: case reports and review of the literature.
作者信息
Bonsen Lisanne R, Aalbersberg Else A, Tesselaar Margot, Stokkel Marcel P M
机构信息
Departments of aNuclear Medicine bMedical Oncology, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
出版信息
Nucl Med Commun. 2016 May;37(5):461-5. doi: 10.1097/MNM.0000000000000464.
BACKGROUND
Most neuroendocrine tumours (NETs) metastasize to the liver, lymph nodes and, although less frequently, to the bone. The heart is a rare localization for NET metastases.
METHODS
With the introduction of the Ga-DOTATATE PET/computed tomography (CT) in our hospital as a new diagnostic method for imaging neuroendocrine tumours, more rare metastatic localizations are being found. We present six cases of patients with cardiac NET metastases detected by Ga-DOTATATE PET/CT. Also, a review of literature is presented on case reports of cardiac NET metastases in patients detected by somatostatin receptor imaging, including In-Pentetreotide single photon emission computed tomography/CT, Ga-DOTATATE PET/CT, Ga-DOTANOC PET/CT or Ga-DOTATOC PET/CT.
RESULTS AND CONCLUSION
Most patients with cardiac NET metastases have extensive metastatic disease. The cardiac metastases are often asymptomatic.
背景
大多数神经内分泌肿瘤（NETs）转移至肝脏、淋巴结，转移至骨的情况较少见。心脏是NET转移的罕见部位。
方法
随着我院引入镓[68Ga] DOTATATE正电子发射断层显像/计算机断层扫描（PET/CT）作为神经内分泌肿瘤的一种新的诊断成像方法，发现了更多罕见的转移部位。我们报告6例通过镓[68Ga] DOTATATE PET/CT检测到心脏NET转移的患者。此外，还对通过生长抑素受体显像检测到的患者心脏NET转移的病例报告进行了文献综述，包括铟[111In] 奥曲肽单光子发射计算机断层扫描/CT、镓[68Ga] DOTATATE PET/CT、镓[68Ga] DOTANOC PET/CT或镓[68Ga] DOTATOC PET/CT。
结果与结论
大多数心脏NET转移患者有广泛的转移性疾病。心脏转移通常无症状。
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