Skoczyński Mariusz, Krzyżanowski Arkadiusz Robert, Goździcka-Józefiak Anna, Kwaśniewska Anna
Department of Obstetrics and Pathology of Pregnancy, Medical University of Lublin.
Adam Mickiewicz University, Institute of Experimental Biology, Department of Molecular Virology.
Postepy Hig Med Dosw (Online). 2015 Dec 16;69:1349-52. doi: 10.5604/17322693.1186332.
The exact route of human papillomavirus (HPV) and herpes simplex virus (HSV) transmission from a pregnant woman to her fetus has not been clearly established thus far. The data of many studies raise the possibility of intrauterine infection. In order to clarify our knowledge about virus vertical transmission in pregnant women, viral prevalence in amniotic fluid cannot. To the best of our knowledge, this is the first study on HPV DNA and HSV DNA detection in amniotic fluid in Poland.
The study covered 138 samples of amniotic fluid from patients undergoing invasive prenatal diagnostic procedures (for medical indications) during the second trimester of gestation. The aim of the study was to assess the prevalence of HPV and HSV in the amniotic fluid samples obtained from asymptomatic women with intact amniotic membranes. To identify viral DNA of HPV and HSV in collected material, polymerase chain reaction (PCR) was performed.
We did not find HPV or HSV DNA in any of the examined specimens of amniotic fluid.
Our investigation did not confirm the prenatal transmission of HPV and HSV to the amniotic fluid.
人乳头瘤病毒（HPV）和单纯疱疹病毒（HSV）从孕妇传播至胎儿的确切途径迄今尚未明确。众多研究数据提示存在宫内感染的可能性。为了阐明我们对孕妇病毒垂直传播的认识，羊水内病毒的流行情况并不清楚。据我们所知，这是波兰第一项关于羊水内HPV DNA和HSV DNA检测的研究。
本研究涵盖了138例妊娠中期接受侵入性产前诊断程序（因医学指征）患者的羊水样本。本研究的目的是评估从羊膜完整的无症状女性获得的羊水样本中HPV和HSV的流行情况。为了鉴定所采集材料中的HPV和HSV病毒DNA，进行了聚合酶链反应（PCR）。
在任何检测的羊水标本中，我们均未发现HPV或HSV DNA。
我们的研究未证实HPV和HSV在产前传播至羊水。
