Pracoń Grzegorz, Płaza Mateusz, Walentowska-Janowicz Marta, Sudoł-Szopińska Iwona
Department of Radiology, Institute of Rheumatology, Warsaw, Poland.
Department of Radiology, Institute of Rheumatology, Warsaw, Poland ; Department of Diagnostic Imaging, Second Faculty, Warsaw Medical University, Poland.
J Ultrason. 2015 Sep;15(62):326-31. doi: 10.15557/JoU.2015.0029. Epub 2015 Sep 30.
Systemic sclerosis, popularly referred to as scleroderma, is a chronic connective tissue disease with present autoantibodies against platelet-derived growth factor receptor. These antibodies activate directly fibroblasts causing the dermis and internal organs' fibrosis and vascular damage. Additionally, calcific collections, including hydroxyapatite crystals, may develop in subcutaneous tissue and juxta-articular soft tissue. Herein, we report a case of a 72-year-old woman, referred by a rheumatologist for plain radiography and ultrasound examination of hands due to pain and swelling of the fourth finger of the left hand. Dermal induration affecting hands, especially fourth finger on the left side and the Raynaud phenomenon were observed on physical examination. Furthermore, the patient had noticed periodic discharge with a toothpaste consistency from a tiny fistula localised in the vicinity of the fourth finger alterations. The paper emphasises a possible application of the twinkling artefact and MicroPure option on ultrasound examination in differential diagnosis of soft tissue calcifications. Making the correct diagnosis can attribute to precise planning of surgical treatment.
系统性硬化症,通常称为硬皮病,是一种慢性结缔组织疾病,目前存在针对血小板衍生生长因子受体的自身抗体。这些抗体直接激活成纤维细胞,导致真皮和内脏器官纤维化以及血管损伤。此外,包括羟基磷灰石晶体在内的钙化沉积物可能在皮下组织和关节周围软组织中形成。在此,我们报告一例72岁女性病例,因左手无名指疼痛和肿胀,由风湿病学家转诊进行手部X线平片和超声检查。体格检查发现手部皮肤硬结,尤其是左侧无名指,以及雷诺现象。此外,患者注意到在无名指病变附近的一个小瘘管有牙膏样的周期性分泌物。本文强调了超声检查中的闪烁伪像和微纯模式在软组织钙化鉴别诊断中的可能应用。做出正确诊断有助于精确规划手术治疗。