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累及胸腹主动脉及主动脉弓的夹层动脉瘤血管腔内修复术的早期经验

Early Experience of Endovascular Repair of Post-dissection Aneurysms Involving the Thoraco-abdominal Aorta and the Arch.

作者信息

Spear R, Sobocinski J, Settembre N, Tyrrell M R, Malikov S, Maurel B, Haulon S

机构信息

Aortic Center, Hôpital Cardiologique, CHRU Lille, France.

Vascular Surgery, CHU Nancy, France.

出版信息

Eur J Vasc Endovasc Surg. 2016 Apr;51(4):488-97. doi: 10.1016/j.ejvs.2015.10.012. Epub 2015 Dec 8.

Abstract

OBJECTIVES

Outcomes are reported in management of post-dissection aneurysms involving the aortic arch and/or thoraco-abdominal segment (TAAA) treated with fenestrated and branched (complex) endografts.

METHODS

This report includes all patients with chronic post-dissection aneurysms >55 mm in diameter, deemed unfit for open surgery, treated using complex endografts between October 2011 and March 2015. When appropriate, staged management strategies including left subclavian artery revascularization, thoracic endografting, dissection flap fenestration or tear enlargement, and other endovascular procedures were performed at least 3 weeks prior to definitive complex endovascular repair. The following outcome data were collected prospectively at discharge, 12 months and annually thereafter: technical success, endoleaks, target vessel patency, false lumen patency, aneurysm diameter, major and minor complications, re-interventions, and mortality.

RESULTS

The cohort comprised 23 patients with a median age of 65 years. Staged procedures were performed in 14 patients (61%). Seven patients with dissections involving the arch were treated with inner branched endografts, and 16 TAAA patients were treated with fenestrated or branched endografts. The technical success rate was 71% following arch repair and 100% following TAAA repair. During early follow up, one of the arch group patients died and one in the TAAA group suffered spinal cord ischemia. The median follow up was 12 months (range 3-48), during which time one patient died of causes unrelated to aneurysm or treatment. Two early re-interventions were performed in the arch group to correct access vessel complications and there were a further two late re-interventions in the TAAA group to treat endoleaks. All target vessels (n = 72) remained patent.

CONCLUSIONS

This experience indicates that complex endovascular repair of post-dissection aneurysms is a viable alternative to open repair in patients deemed unfit for open surgery. There are insufficient data to allow comparison with the outcome of open surgery in anatomically similar, but fit, patients.

摘要

目的

报告采用开窗和分支(复杂)内移植物治疗累及主动脉弓和/或胸腹段(TAAA)的夹层后动脉瘤的治疗结果。

方法

本报告纳入了2011年10月至2015年3月期间所有直径>55 mm、被认为不适合开放手术的慢性夹层后动脉瘤患者,采用复杂内移植物进行治疗。在适当情况下,在确定性复杂血管内修复至少3周前,进行分期管理策略,包括左锁骨下动脉血运重建、胸段内移植物植入、夹层瓣开窗或裂口扩大以及其他血管内手术。以下结局数据在出院时、12个月时及此后每年前瞻性收集:技术成功率、内漏、靶血管通畅情况、假腔通畅情况、动脉瘤直径、主要和次要并发症、再次干预及死亡率。

结果

该队列包括23例患者,中位年龄65岁。14例患者(61%)进行了分期手术。7例累及主动脉弓的夹层患者接受了内置分支内移植物治疗,16例TAAA患者接受了开窗或分支内移植物治疗。主动脉弓修复后的技术成功率为71%,TAAA修复后的技术成功率为100%。在早期随访期间,主动脉弓组有1例患者死亡,TAAA组有1例患者发生脊髓缺血。中位随访时间为12个月(范围3 - 48个月),在此期间,1例患者死于与动脉瘤或治疗无关的原因。主动脉弓组进行了2次早期再次干预以纠正入路血管并发症,TAAA组又进行了2次晚期再次干预以治疗内漏。所有靶血管(n = 72)均保持通畅。

结论

该经验表明,对于被认为不适合开放手术的患者,夹层后动脉瘤的复杂血管内修复是开放修复的可行替代方案。目前尚无足够数据与解剖结构相似但适合开放手术的患者的开放手术结果进行比较。

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