Christian E P, Bosse M J, Robb G
Department of Orthopedic Surgery, Naval Hospital, Portsmouth, Virginia 23708.
J Bone Joint Surg Am. 1989 Aug;71(7):994-1004.
Eight Grade-IIIB tibial fractures that were associated with large soft-tissue and segmental diaphyseal defects, averaging ten centimeters in length, were successfully reconstructed without the use of a free fibular transfer. A free tissue flap was the preferred form of soft-tissue coverage. The osseous reconstruction was accomplished by using a massive amount of autogenous cancellous bone graft. Beads that were made from polymethylmethacrylate and impregnated with two antibiotics at the time of operation were used as soft-tissue spacers to preserve the volume of the diaphyseal defect for later receipt of the cancellous bone graft. The beads prevented the soft-tissue flap from collapsing into and adhering to the site of the tibial defect. The beads also served as vehicles for local delivery of the antibiotics that they contained. When the soft-tissue flap had healed, the beads were replaced with cancellous graft. All of the tibiae healed. The time to healing averaged nine months. The average duration of external fixation was 5.5 months. One deep infection developed, but resolved after debridement and antibiotic therapy. This conservative technique is safe and reliable for patients who have sustained a high-energy tibial fracture and a large segmental diaphyseal defect.
8例伴有大面积软组织和骨干节段性缺损(平均长度为10厘米)的ⅢB级胫骨骨折,在未使用游离腓骨移植的情况下成功重建。游离组织瓣是软组织覆盖的首选形式。骨重建通过使用大量自体松质骨移植完成。在手术时,由聚甲基丙烯酸甲酯制成并浸渍两种抗生素的珠子被用作软组织间隔物,以保持骨干缺损的容积,以便后期接受松质骨移植。这些珠子可防止软组织瓣塌陷并粘附于胫骨缺损部位。珠子还作为其所含抗生素局部递送的载体。当软组织瓣愈合后,将珠子替换为松质骨移植物。所有胫骨均愈合。愈合时间平均为9个月。外固定的平均持续时间为5.5个月。发生了1例深部感染,但在清创和抗生素治疗后得到解决。对于遭受高能胫骨骨折和大面积骨干节段性缺损的患者,这种保守技术是安全可靠的。