College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China.
College of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350108, PR China.
Carbohydr Polym. 2016 Feb 10;137:410-417. doi: 10.1016/j.carbpol.2015.10.098. Epub 2015 Nov 9.
The interactions of succinylated collagen (SC) and carboxymethyl cellulose (CMC) in neutral solutions (pH ∼ 6.9) were investigated, which could provide information for the fields of tissue engineering and cosmetics. According to the results from viscometric measurements, the SC and CMC molecules were possibly compatible as CMC ≤ 50%. Ultrasensitive microcalorimetry reflected the increase in the values of transition temperature (Tm) and heat capacity change (ΔCp) as CMC ≤ 50%, while both of them decreased as the CMC content further increased. Two-dimensional Fourier transform infrared spectroscopy analysis confirmed the hydrogen bonding and electrostatic interactions between SC and CMC, and the hydrogen bonding interaction played a key role as CMC ≤ 50%, while electrostatic interaction became predominant as more CMC was added. Atomic force morphology revealed the changes in the aggregation of SC induced by the addition of CMC.
研究了中性溶液（pH∼6.9）中琥珀酰化胶原（SC）和羧甲基纤维素（CMC）的相互作用，这可为组织工程和化妆品领域提供信息。根据粘度测量结果，SC 和 CMC 分子可能是相容的，只要 CMC≤50%。超灵敏微量量热法反映出当 CMC≤50%时，转变温度（Tm）和热容变化（ΔCp）的值增加，而当 CMC 含量进一步增加时，它们都降低。二维傅里叶变换红外光谱分析证实了 SC 和 CMC 之间的氢键和静电相互作用，并且当 CMC≤50%时，氢键相互作用起关键作用，而随着添加更多的 CMC，静电相互作用变得占主导地位。原子力形貌揭示了添加 CMC 引起的 SC 聚集的变化。
