Burmen B, Modi S, Cavanaugh J S, Muttai H, McCarthy K D, Alexander H, Cain K
Kenya Medical Research Institute (KEMRI), Center for Global Health Research, Kisumu, Kenya; KEMRI/Centers for Disease Control and Prevention (CDC) Research and Public Health Collaboration, Kisumu, Kenya.
US CDC, Atlanta, Georgia, USA.
Int J Tuberc Lung Dis. 2016 Jan;20(1):79-84. doi: 10.5588/ijtld.15.0053.
Fifteen human immunodeficiency virus (HIV) clinics in Nyanza Region, Western Kenya.
To describe routine tuberculosis (TB) screening and diagnostic practices among newly enrolled people living with HIV (PLHIV) prior to the implementation of World Health Organization recommended TB intensified case finding.
Retrospective chart abstraction of PLHIV aged ⩾7 years who were newly enrolled in HIV care in July and August 2009, and who had not received antiretroviral treatment in the preceding 2 years or been diagnosed with TB in the previous year. Factors associated with evidence of TB diagnostic evaluation among symptomatic PLHIV were assessed.
Of 1020 patients included in the analysis, 995 (98%) were screened for TB at enrolment and 613 (62%) reported TB symptoms. Ninety-six (16%) patients with symptoms had evidence of referral for TB diagnostic evaluation, including patients at large clinics, those with advanced HIV disease and those reporting multiple TB symptoms. Among the 43 (45%) with documented evaluation results, 26 (60%) were diagnosed with TB.
Although most PLHIV were screened for TB, very few underwent an evaluation, and the proportion diagnosed with TB was very low. Efforts to improve TB screening should focus on standardizing the intensified case finding algorithm and linkage to, and adequate infrastructure for, TB diagnostic evaluation.
肯尼亚西部尼扬扎地区的15家人类免疫缺陷病毒(HIV)诊所。
描述在实施世界卫生组织推荐的结核病强化病例发现之前,新登记的HIV感染者(PLHIV)中的常规结核病筛查和诊断做法。
对2009年7月和8月新登记接受HIV治疗、在过去2年未接受抗逆转录病毒治疗或上一年未被诊断为结核病的7岁及以上PLHIV进行回顾性病历摘要分析。评估有症状的PLHIV中与结核病诊断评估证据相关的因素。
纳入分析的1020例患者中,995例(98%)在登记时接受了结核病筛查,613例(62%)报告有结核病症状。96例(16%)有症状的患者有被转诊进行结核病诊断评估的证据,包括大型诊所的患者、患有晚期HIV疾病的患者以及报告有多种结核病症状的患者。在43例(45%)有记录评估结果的患者中,26例(60%)被诊断为结核病。
虽然大多数PLHIV接受了结核病筛查,但很少有人接受评估,被诊断为结核病的比例非常低。改善结核病筛查的努力应集中在标准化强化病例发现算法以及与结核病诊断评估的联系和充足的基础设施上。