Khan Sabeen Abid, Ibrahim Mohsina Noor
Department of Paediatrics, The Aga Khan University Hospital, Karachi.
Department of Paediatrics, National Institute of Child Health, Karachi.
J Coll Physicians Surg Pak. 2015 Dec;25(12):878-81.
To determine the frequency of hyperglycemia in critically ill children admitted in PICU of a tertiary care hospital of Karachi and to compare the mortality of critically ill children with and without hyperglycemia.
Cross-sectional study.
Paediatrics Intensive Care Unit (PICU) of National Institute of Child Health (NICH), Karachi, from November 2011 to April 2012.
One hundred fifty critically ill children admitted to PICU were included. Patients who had fasting blood sugar levels more than 126 mg/dl within 48 hours of admission were included in the hyperglycemic group. The normoglycemic and hyperglycemic groups were followed till 10 days to determine the mortality associated with hyperglycemia.
Out of 150 patients, 82 (54.7%) had hyperglycemia. Mortality rate was 48.7% (n=73/150). However, mortality rate was significantly high 57.3% (n=47) in hyperglycemic patients than non-hyperglycemic patients (p=0.019).
The presence of stress-induced hyperglycemia in critically ill patients is a well established marker of poor outcome, and a very high mortality rate. Normoglycemia was associated with favorable outcomes in terms of hospital stay and mortality.
确定卡拉奇一家三级医疗医院儿科重症监护病房（PICU）收治的危重症患儿高血糖的发生率，并比较有高血糖和无高血糖的危重症患儿的死亡率。
横断面研究。
2011年11月至2012年4月，卡拉奇国家儿童健康研究所（NICH）的儿科重症监护病房（PICU）。
纳入150名入住PICU的危重症患儿。入院48小时内空腹血糖水平超过126mg/dl的患者被纳入高血糖组。对血糖正常组和高血糖组进行为期10天的随访，以确定与高血糖相关的死亡率。
150例患者中，82例（54.7%）有高血糖。死亡率为48.7%（n=73/150）。然而，高血糖患者的死亡率显著高于非高血糖患者，为57.3%（n=47）（p=0.019）。
危重症患者中应激性高血糖的存在是预后不良和死亡率极高的一个公认标志。血糖正常在住院时间和死亡率方面与良好预后相关。
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