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系统性红斑狼疮患者中模仿脉络膜肿瘤的结节性后巩膜炎:一例报告及文献综述

Nodular Posterior Scleritis Mimicking Choroidal Tumor in a Patient With Systemic Lupus Erythematous: A Case Report and Literature Review.

作者信息

Sin Pui Yee, Liu David Ta Li, Young Alvin L

机构信息

From the *Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital; and †Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

出版信息

Asia Pac J Ophthalmol (Phila). 2016 Sep-Oct;5(5):324-9. doi: 10.1097/APO.0000000000000165.

Abstract

PURPOSE

Posterior scleritis is a potentially blinding ocular disorder that is often difficult to diagnose because of the low incidence and varied clinical presentation. Nodular posterior scleritis can mimic a choroidal mass and pose diagnostic difficulties to clinicians. This case report and literature review aimed to evaluate the clinical presentation of nodular posterior scleritis that mimics choroidal tumor, along with the etiologies, treatment modalities, and outcomes.

DESIGN

Case report and literature review.

METHODS

We describe a case of nodular posterior scleritis that presented as a choroidal mass in a patient with systemic lupus erythematous. Previous reports on nodular posterior scleritis presenting as choroidal mass were reviewed.

RESULTS

Including this case, there were 14 cases of nodular posterior scleritis presenting as a choroidal mass in the past 20 years. The mean age was 50 years, with women being predominant (79%). All cases had unilateral eye involvement. Most patients presented with a drop in vision (ranging from counting fingers to visual acuity of 20/30). The cause was mostly idiopathic in 79% of reported cases. Most patients (71%) were treated with a course of systemic steroids. Two patients required systemic steroids together with immunosuppressive agents. Most patients responded to treatment with visual recovery and resolution of the choroidal mass.

CONCLUSIONS

Nodular posterior scleritis is a rare disease that can easily be confused with choroidal tumor. Associated ocular pain is a useful feature for differentiating nodular posterior scleritis from other forms of choroidal masses. Early diagnosis and prompt treatment usually can deliver a good outcome.

摘要

目的

后巩膜炎是一种可能致盲的眼部疾病,由于发病率低且临床表现多样,常常难以诊断。结节性后巩膜炎可酷似脉络膜肿物,给临床医生带来诊断难题。本病例报告及文献综述旨在评估酷似脉络膜肿瘤的结节性后巩膜炎的临床表现、病因、治疗方式及预后。

设计

病例报告及文献综述。

方法

我们描述了一例系统性红斑狼疮患者出现的以脉络膜肿物形式表现的结节性后巩膜炎病例。对既往关于以脉络膜肿物形式表现的结节性后巩膜炎的报告进行了回顾。

结果

包括本病例在内,过去20年中有14例以脉络膜肿物形式表现的结节性后巩膜炎病例。平均年龄为50岁,女性占多数(79%)。所有病例均为单眼受累。大多数患者出现视力下降(从指数到视力20/30不等)。在报告的病例中,79%的病因大多为特发性。大多数患者(71%)接受了一个疗程的全身类固醇治疗。两名患者需要全身类固醇联合免疫抑制剂治疗。大多数患者经治疗后视力恢复,脉络膜肿物消退。

结论

结节性后巩膜炎是一种罕见疾病,容易与脉络膜肿瘤混淆。相关的眼痛是将结节性后巩膜炎与其他形式的脉络膜肿物相鉴别的有用特征。早期诊断和及时治疗通常可取得良好预后。

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