Konstantinov K, Kolarski V, Kaleva M, Diankova L, Petrova D
Vutr Boles. 1989;28(2):72-7.
The degree of the filling up and the dilation of the gall bladder, its functional state as well as the passibility of d. cysticus are evaluated by ultrasound examination and computer determination of the surface and dimensions of the gall bladder. 546 patients, 20-78 years of age (484 women and 62 men) were examined by a pharmacodynamic functional test with chologon (acidum dehydrocholicum) in a dose of 10 mg/kg body mass and sorbitol (in 116 patients) in a dose of 20 g in 100 ml of water. The functional test is easily performed in the course of the ultrasound examination and side effects were registered. The test allows the assessment of the functional state of the gall bladder, the passibility of d. cysticus, the degree and mechanism of the filling up of the gall bladder and the bile ducts with bile. The better filling up of the gall bladder with bile after application of chologon (by passable d. cysticus) ensures better conditions for detecting microgallstones in the gall bladder as well as of diseases linked with its wall--cholesterosis, cancer and polypi of the bladder, etc.
通过超声检查以及计算机测定胆囊的表面积和尺寸，评估胆囊的充盈度、扩张程度、功能状态以及胆囊管的通畅性。对546例年龄在20至78岁之间的患者（484例女性和62例男性）进行了药效学功能测试，使用剂量为10mg/kg体重的胆影酸（去氢胆酸），116例患者还使用了剂量为20g溶于100ml水中的山梨醇。该功能测试在超声检查过程中易于进行，并记录了副作用。该测试可评估胆囊的功能状态、胆囊管的通畅性、胆囊和胆管胆汁充盈的程度及机制。注射胆影酸后胆囊胆汁充盈更佳（通过通畅的胆囊管），为检测胆囊内的微小结石以及与胆囊壁相关的疾病——胆固醇沉着症、胆囊癌和息肉等创造了更好的条件。
