减少痴呆症行为和心理症状的非药物干预措施：一项系统综述。
Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review.
作者信息
de Oliveira Alexandra Martini, Radanovic Marcia, de Mello Patrícia Cotting Homem, Buchain Patrícia Cardoso, Vizzotto Adriana Dias Barbosa, Celestino Diego L, Stella Florindo, Piersol Catherine V, Forlenza Orestes V
机构信息
Laboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, 05403-010 São Paulo, SP, Brazil ; Occupational Therapy Service, Institute of Psychiatry, Faculty of Medicine, University of São Paulo, 05403-010 São Paulo, SP, Brazil.
Laboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, 05403-010 São Paulo, SP, Brazil.
出版信息
Biomed Res Int. 2015;2015:218980. doi: 10.1155/2015/218980. Epub 2015 Nov 29.
INTRODUCTION
Behavioral and psychological symptoms of dementia (BPSD) are defined as a group of symptoms of disturbed perceptive thought content, mood, or behavior that include agitation, depression, apathy, repetitive questioning, psychosis, aggression, sleep problems, and wandering. Care of patients with BPSD involves pharmacological and nonpharmacological interventions. We reviewed studies of nonpharmacological interventions published in the last 10 years.
METHODS
We performed a systematic review in Medline and Embase databases, in the last 10 years, until June 2015. Key words used were (1) non-pharmacological interventions, (2) behavioral symptoms, (3) psychological symptoms, and (4) dementia.
RESULTS
We included 20 studies published in this period. Among these studies, program activities were more frequent (five studies) and the symptoms more responsive to the interventions were agitation.
DISCUSSION
Studies are heterogeneous in many aspects, including size sample, intervention, and instruments of measures.
CONCLUSION
Nonpharmacological interventions are able to provide positive results in reducing symptoms of BPSD. Most studies have shown that these interventions have important and significant efficacy.
引言
痴呆的行为和心理症状（BPSD）被定义为一组感知、思维内容、情绪或行为紊乱的症状，包括激动、抑郁、冷漠、反复提问、精神病、攻击行为、睡眠问题和徘徊。对患有BPSD的患者的护理涉及药物和非药物干预。我们回顾了过去10年发表的关于非药物干预的研究。
方法
我们在截至2015年6月的过去10年里，对Medline和Embase数据库进行了系统回顾。使用的关键词为：（1）非药物干预；（2）行为症状；（3）心理症状；（4）痴呆。
结果
我们纳入了这一时期发表的20项研究。在这些研究中，项目活动更为常见（五项研究），对干预反应更明显的症状是激动。
讨论
研究在许多方面存在异质性，包括样本量、干预措施和测量工具。
结论
非药物干预能够在减轻BPSD症状方面取得积极效果。大多数研究表明，这些干预措施具有重要且显著的疗效。
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