Ferzoco Raina M, Ruddy Kathryn J
Department of Oncology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Curr Oncol Rep. 2016 Jan;18(1):1. doi: 10.1007/s11912-015-0487-4.
Male breast cancer is a rare disease, accounting for only 1% of breast cancer diagnoses in the USA. The current literature suggests that genetic factors including BRCA2 mutations, family history, age, androgen/estrogen imbalance, and environmental exposures may predispose to male breast cancer. In this manuscript, we will review known and possible risk factors for male breast cancer, as well as describe the clinical patterns of the disease.
男性乳腺癌是一种罕见疾病,在美国仅占乳腺癌诊断病例的1%。当前文献表明,包括BRCA2突变、家族史、年龄、雄激素/雌激素失衡以及环境暴露等遗传因素可能易患男性乳腺癌。在本论文中,我们将回顾男性乳腺癌已知和可能的风险因素,并描述该疾病的临床特征。