Chen Yajun, Lan Tao, Duan Lunchao, Wang Fenghe, Zhao Bin, Zhang Shengtian, Wei Wei
Jiangsu Provincial Key Laboratory of Materials Cycling and Pollution Control, School of Geography Science, Nanjing Normal University, Nanjing, 210023, China.
Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application, Nanjing, 210023, China.
PLoS One. 2015 Dec 23;10(12):e0145025. doi: 10.1371/journal.pone.0145025. eCollection 2015.
Various kinds of antibiotics, especially fluoroquinolone antibiotics (FQs) have been widely used for the therapy of infectious diseases in human and livestock. For their poorly absorbed by living organisms, large-scale misuse or abuse of FQs will foster drug resistance among pathogenic bacteria, as well as a variety of environmental problems when they were released in the environment. In this work, the adsorption properties of two FQs, namely norfloxacin (NOR) and ciprofloxacin (CIP), by nano-hydroxyapatite (n-HAP) were studied by batch adsorption experiments. The adsorption curves of FQs by n-HAP were simulated by Langmuir and Freundlich isotherms. The results shown that NOR and CIP can be adsorbed effectively by the adsorbent of n-HAP, and the adsorption capacity of FQs increase with increasing dosage of n-HAP. The optimum dosage of n-HAP for FQs removal was 20 g · L(-1), in which the removal efficiencies is 51.6% and 47.3%, and an adsorption equilibrium time is 20 min. The maximum removal efficiency occurred when pH is 6 for both FQs. The adsorption isotherm of FQs fits well for both Langmuir and Freundlich equations. The adsorption of both FQs by n-HAP follows second-order kinetics.
各种抗生素，尤其是氟喹诺酮类抗生素（FQs）已被广泛用于人类和牲畜传染病的治疗。由于它们在生物体内吸收较差，FQs的大规模误用或滥用会助长病原菌的耐药性，以及当它们释放到环境中时会引发各种环境问题。在这项工作中，通过批量吸附实验研究了纳米羟基磷灰石（n-HAP）对两种FQs，即诺氟沙星（NOR）和环丙沙星（CIP）的吸附特性。用Langmuir和Freundlich等温线模拟了n-HAP对FQs的吸附曲线。结果表明，NOR和CIP能被n-HAP吸附剂有效吸附，FQs的吸附量随n-HAP用量的增加而增加。去除FQs的n-HAP最佳用量为20 g·L(-1)，其中去除效率分别为51.6%和47.3%，吸附平衡时间为20分钟。两种FQs在pH为6时去除效率最高。FQs的吸附等温线与Langmuir和Freundlich方程都拟合良好。n-HAP对两种FQs的吸附均符合二级动力学。
