Coca-Pelaz Andrés, Gómez-Martínez Justo, Vivanco-Allende Blanca, Hermsen Mario, Llorente Jose Luis
Department of Otorhinolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Department of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Head Neck. 2016 May;38(5):E105-7. doi: 10.1002/hed.24329. Epub 2015 Dec 24.
Primary inverted papillomas of the middle ear are extremely rare tumors, with only few cases published in the literature. They have a characteristic epithelium surface inversion to the inside of the stroma. Inverted papillomas are benign lesions but have a high propensity of recurrence, local aggressiveness, and association with malignancy.
We present a patient with an inverted papilloma originating in the middle ear producing chronic otorrhea and facial nerve palsy treated with a subtotal petrosectomy.
During the follow-up, the patient developed an intracranial invasion of the tumor causing his death.
Primary inverted papillomas of the middle ear can have an extremely aggressive behavior despite their benign characteristics; therefore, an aggressive treatment must be performed in order to minimize the possibility of recurrence.
中耳原发性内翻性乳头状瘤是极其罕见的肿瘤，文献中仅报道了少数病例。它们具有特征性的上皮表面向间质内部反转。内翻性乳头状瘤是良性病变，但具有高复发倾向、局部侵袭性以及与恶性肿瘤相关。
我们报告了一名患有起源于中耳的内翻性乳头状瘤的患者，该肿瘤导致慢性耳漏和面瘫，接受了颞骨次全切除术治疗。
在随访期间，患者发生肿瘤颅内侵犯并导致死亡。
中耳原发性内翻性乳头状瘤尽管具有良性特征，但可能具有极其侵袭性的行为；因此，必须进行积极治疗以尽量减少复发的可能性。
