Suppr超能文献

一种基于放射变色胶片测量的放射治疗质量保证新传输方法。

A new transmission methodology for quality assurance in radiotherapy based on radiochromic film measurements.

作者信息

do Amaral Leonardo L, de Oliveira Harley F, Pavoni Juliana F, Sampaio Franciso, Ghillardi Netto Thomaz

机构信息

Sciences and Letters of Ribeirão Preto University of São Paulo.

出版信息

J Appl Clin Med Phys. 2015 Sep 8;16(5):1-12. doi: 10.1120/jacmp.v16i5.5497.

Abstract

Despite individual quality assurance (QA) being recommended for complex techniques in radiotherapy (RT) treatment, the possibility of errors in dose delivery during therapeutic application has been verified. Therefore, it is fundamentally important to conduct in vivo QA during treatment. This work presents an in vivo transmission quality control methodology, using radiochromic film (RCF) coupled to the linear accelerator (linac) accessory holder. This QA methodology compares the dose distribution measured by the film in the linac accessory holder with the dose distribution expected by the treatment planning software. The calculated dose distribution is obtained in the coronal and central plane of a phantom with the same dimensions of the acrylic support used for positioning the film but in a source-to-detector distance (SDD) of 100 cm, as a result of transferring the IMRT plan in question with all the fields positioned with the gantry vertically, that is, perpendicular to the phantom. To validate this procedure, first of all a Monte Carlo simulation using PENELOPE code was done to evaluate the differences between the dose distributions measured by the film in a SDD of 56.8 cm and 100 cm. After that, several simple dose distribution tests were evaluated using the proposed methodology, and finally a study using IMRT treatments was done. In the Monte Carlo simulation, the mean percentage of points approved in the gamma function comparing the dose distribution acquired in the two SDDs were 99.92% ± 0.14%. In the simple dose distribution tests, the mean percentage of points approved in the gamma function were 99.85% ± 0.26% and the mean percentage differences in the normalization point doses were -1.41%. The transmission methodology was approved in 24 of 25 IMRT test irradiations. Based on these results, it can be concluded that the proposed methodology using RCFs can be applied for in vivo QA in RT treatments.

摘要

尽管对于放射治疗(RT)中的复杂技术推荐进行个体质量保证(QA),但在治疗应用过程中剂量输送出现误差的可能性已得到证实。因此,在治疗期间进行体内QA至关重要。本研究提出一种体内传输质量控制方法,使用与直线加速器(linac)附件支架耦合的放射变色胶片(RCF)。这种QA方法将胶片在linac附件支架中测量的剂量分布与治疗计划软件预期的剂量分布进行比较。通过将相关调强放疗(IMRT)计划转移到源皮距(SDD)为100 cm、所有射野均使机架垂直定位(即垂直于模体)的情况下,在与用于放置胶片的丙烯酸支撑体尺寸相同的模体的冠状面和中心平面上获得计算剂量分布。为验证该程序,首先使用PENELOPE代码进行蒙特卡罗模拟,以评估胶片在56.8 cm和100 cm SDD下测量的剂量分布之间的差异。之后,使用所提出的方法评估了几个简单剂量分布测试,最后进行了一项使用IMRT治疗的研究。在蒙特卡罗模拟中,比较在两个SDD下获得的剂量分布的伽马函数中批准点的平均百分比为99.92%±0.14%。在简单剂量分布测试中,伽马函数中批准点的平均百分比为99.85%±0.26%,归一化点剂量的平均百分比差异为 -1.41%。在25次IMRT测试照射中有24次批准了传输方法。基于这些结果,可以得出结论,所提出的使用RCF的方法可应用于RT治疗中的体内QA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d36a/5690170/605057439c75/ACM2-16-001a-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验