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首发精神病中的语言障碍和功能障碍。

Language disturbance and functioning in first episode psychosis.

机构信息

Dublin and East Treatment and Early Care Team (DETECT) Service, Blackrock, Co Dublin, Ireland; School of Medicine and Medical Sciences, University College Dublin, Belfield, Dublin, Ireland.

UCD CSTAR, School of Public Health, Physiotherapy and Population Science, University College Dublin, Belfield, Dublin, Ireland.

出版信息

Psychiatry Res. 2016 Jan 30;235:29-37. doi: 10.1016/j.psychres.2015.12.008. Epub 2015 Dec 9.

Abstract

Language disturbance has a central role in the presentation of psychotic disorders however its relationship with functioning requires further clarification, particularly in first episode psychosis (FEP). Both language disturbance and functioning can be evaluated with clinician-rated and performance-based measures. We aimed to investigate the concurrent association between clinician-rated and performance-based measures of language disturbance and functioning in FEP. We assessed 108 individuals presenting to an Early Intervention in Psychosis Service in Ireland. Formal thought disorder (FTD) dimensions and bizarre idiosyncratic thinking (BIT) were rated with structured assessment tools. Functioning was evaluated with a performance-based instrument, a clinician-rated measure and indicators of real-world functioning. The disorganisation dimension of FTD was significantly associated with clinician-rated measures of occupational and social functioning (Beta=-0.19, P<0.05 and Beta=-0.31, P<0.01, respectively). BIT was significantly associated with the performance-based measure of functioning (Beta=-0.22, P<0.05). Language disturbance was of less value in predicting real-world measures of functioning. Clinician-rated and performance-based assessments of language disturbance are complementary and each has differential associations with functioning. Communication disorders should be considered as a potential target for intervention in FEP, although further evaluation of the longitudinal relationship between language disturbance and functioning should be undertaken.

摘要

语言障碍在精神障碍的表现中起着核心作用,但它与功能的关系需要进一步澄清,特别是在首发精神病(FEP)中。语言障碍和功能都可以通过临床医生评估和基于表现的测量来评估。我们旨在研究 FEP 中临床医生评估和基于表现的语言障碍和功能测量的并发关联。我们评估了爱尔兰一家早期精神病干预服务机构的 108 名患者。使用结构化评估工具评估了思维形式障碍(FTD)的各个维度和奇特的独特思维(BIT)。使用基于表现的工具、临床医生评估的量表和现实世界功能的指标来评估功能。FTD 的紊乱维度与临床医生评估的职业和社会功能量表显著相关(Beta=-0.19,P<0.05 和 Beta=-0.31,P<0.01)。BIT 与功能的基于表现的测量显著相关(Beta=-0.22,P<0.05)。语言障碍在预测现实世界的功能测量方面的价值较低。语言障碍的临床评估和基于表现的评估是互补的,并且每个评估都与功能有不同的关联。在 FEP 中,应考虑将沟通障碍作为干预的潜在目标,尽管应进一步评估语言障碍和功能之间的纵向关系。

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