Department of Pediatrics, Divisions of Infectious Diseases and Neonatal/Perinatal Medicine, Texas A&M Health Science Center College of Medicine, Baylor Scott & White Health, 1901 SW HK Dodgen Loop, Temple, TX, 76502, USA.
Department of Pediatrics, Division of Pediatric Inpatient Medicine, Texas A&M Health Science Center College of Medicine, Baylor Scott & White Health, 1901 SW HK Dodgen Loop, Temple, TX, 76502, USA.
Curr Infect Dis Rep. 2016 Jan;18(1):1. doi: 10.1007/s11908-015-0508-3.
We reviewed the literature regarding bacteremia in early infancy (age ≤ 90 days). Bacteremia remains a major cause of morbidity and mortality in young infants. However, recent epidemiologic data suggest that the incidence of bacteremia is decreasing and the pathogens responsible for invasive disease are changing. These changes will impact the evaluation and management of young infants. We review the current epidemiology of community-acquired bacteremia in early infancy with particular emphasis on the causative agents, diagnostic evaluation, and empiric and definitive antimicrobial treatment.
我们回顾了有关婴儿早期(≤ 90 天)菌血症的文献。菌血症仍然是婴儿发病和死亡的主要原因。然而,最近的流行病学数据表明,菌血症的发病率正在下降,引起侵袭性疾病的病原体也在发生变化。这些变化将影响对婴儿的评估和管理。我们回顾了目前婴儿早期社区获得性菌血症的流行病学,特别强调了病原体、诊断评估以及经验性和确定性抗菌治疗。