Bauer Annette, Knapp Martin, Parsonage Michael
Personal Social Services Research Unit, London School of Economics and Political Science, Houghton Street, London WC2A 2AE, UK.
Personal Social Services Research Unit, London School of Economics and Political Science, Houghton Street, London WC2A 2AE, UK.
J Affect Disord. 2016 Mar 1;192:83-90. doi: 10.1016/j.jad.2015.12.005. Epub 2015 Dec 15.
Anxiety and depression are common among women during pregnancy and the year after birth. The consequences, both for the women themselves and for their children, can be considerable and last for many years. This study focuses on the economic consequences, aiming to estimate the total costs and health-related quality of life losses over the lifetime of mothers and their children.
A pathway or decision modelling approach was employed, based on data from previous studies. Systematic and pragmatic literature reviews were conducted to identify evidence of impacts of perinatal anxiety and depression on mothers and their children.
The present value of total lifetime costs of perinatal depression (anxiety) was £75,728 (£34,811) per woman with condition. If prevalence estimates were applied the respective cost of perinatal anxiety and depression combined was about £8500 per woman giving birth; for the United Kingdom, the aggregated costs were £6.6 billion. The majority of the costs related to adverse impacts on children and almost a fifth were borne by the public sector.
The method was exploratory in nature, based on a diverse range of literature and encountered important data gaps.
Findings suggest the need to allocate more resources to support women with perinatal mental illness. More research is required to understand the type of interventions that can reduce long-term negative effects for both mothers and offspring.
焦虑和抑郁在孕期女性及产后一年内很常见。其后果，无论是对女性自身还是对其子女，都可能相当严重且会持续多年。本研究聚焦于经济后果，旨在估算母亲及其子女一生中的总成本以及与健康相关的生活质量损失。
基于先前研究的数据，采用了路径或决策建模方法。进行了系统且务实的文献综述，以确定围产期焦虑和抑郁对母亲及其子女影响的证据。
患有围产期抑郁症（焦虑症）的每位女性一生总成本的现值为75,728英镑（34,811英镑）。如果应用患病率估算，围产期焦虑和抑郁合并的各自成本约为每位分娩女性8500英镑；就英国而言，总计成本为66亿英镑。大部分成本与对子女的不利影响相关，近五分之一由公共部门承担。
该方法本质上具有探索性，基于多种文献且存在重要的数据缺口。
研究结果表明需要分配更多资源来支持患有围产期精神疾病的女性。需要更多研究来了解能够减少对母亲和后代长期负面影响的干预措施类型。
