Pawar Satyajit, Ragesh R, Nischal Neeraj, Sharma Sanchit, Panda Prasan Kumar, Sharma S K
J Assoc Physicians India. 2015 Jun;63(6):65-8.
India and neighboring Nepal, Bangladesh along with Sudan and Brazil are the four largest foci of visceral leishmaniasis and account for 90% of the world's visceral leishmaniasis (VL) burden, with India being the worst affected. High degree of suspicion is usually based on patient presenting from endemic area with features of pancytopenia hepatosplenomegaly. Hemophagocytic lymphohistiocytic (HLH) syndrome also presents with similar clinical features. Visceral leishmaniasis leading to secondary HLH syndrome is in itself a rare entity while both of these presenting in pregnant patient, to the best knowledge of the authors, is yet to be described in literature.
印度及其邻国尼泊尔、孟加拉国以及苏丹和巴西是内脏利什曼病的四大主要疫源地,占全球内脏利什曼病负担的90%,其中印度受影响最为严重。高度怀疑通常基于来自流行地区且有全血细胞减少、肝脾肿大特征的患者。噬血细胞性淋巴组织细胞增生症(HLH)综合征也有类似的临床特征。导致继发性HLH综合征的内脏利什曼病本身是一种罕见疾病,而就作者所知,这两种疾病同时出现在孕妇身上的情况在文献中尚未有描述。