[Evaluation of Crohn's disease activity with multi-slice CT enterography].

OBJECTIVE

To discuss the diagnostic value of Crohn's disease activity with multi-slice CT enterography.

METHODS

MSCTE examination data of 88 cases of CD patients by clinical, endoscopy, pathology confirmed in Sir Run Run Shaw Hospital from January 2013 to June 2014 were analysed. According to the Harvey-Bradshaw index, all of CD patients were divided into the active phase group and remission phase group. Imaging findings of two groups were compared. To explore the relationship between MSCTE findings and CRP/ESR of CD patients.

RESULTS

The wall thickness (8.2 ± 2.6) mm and enhancement degree (112 ± 16) HU in active phase group were higher than the wall thickness (5.4 ± 1.6) mm and enhancement degree (93 ± 17) HU in the remission phase group (P < 0.01). The incidences of intestinal wall stratification enhancement, comb sign, swollen lymph nodes, phlegmon, intestinal fistula, intestinal stenosis in active phase group (88.5%, 72.1%, 77%, 45.9%, 26.2%, 65.6%) were significantly higher than those in remission phase group (29.6%, 18.5%, 25.9%, 0, 3.7%, 37%) (P < 0.05). The incidences of intestinal wall homogeneous enhancement in remission phase group (70.4%) were higher than those in active phase group (11.5%) (P < 0.01). There was no significant difference in the incidences of abscesse in two groups (P > 0.05). CRP was correlated with the wall thickness and enhancement degree, abnornlal mesentery vascularity, lymph node enlargement, phlegmon, intestinal fistula (r > 0.2, P < 0.05). ESR was correlated with the wall enhancement degree, abnormal mesentery vascularity, lymph node enlargement and phlegmon (r > 0.2, P < 0.05).

CONCLUSION

CT enterography can adequately demonstrate mural abnormalities and assess the presence of extramural complications, which are helpful in evaluating the activity of Crohn's disease.