Gleckman R A
University of Massachusetts Medical School, Worcester.
Infect Dis Clin North Am. 1989 Sep;3(3):507-16.
There are unique challenges for the physician who prescribes an antibiotic to an elderly patient. Advanced age is associated with physiological alterations and a reduction in the excretion of numerous compounds. Mental and physical illness in aged patients will impair unsupervised drug compliance. Antibiotic-related adverse events and antibiotic-associated drug interactions pose a threat to life and impede the desired therapeutic outcome.
