Comparative study between latex agglutination and indirect immunofluorescent antibody tests in diagnosis of toxoplasmosis.

The latex agglutination test (Toxolatex) was compared with the indirect immunofluorescent antibody test (IFAT) in investigating one hundred and fifty human sera. Both techniques showed 90.7% agreement. The mean titre of each test was significantly higher in cases with fever or lymphadenopathy than cases without these manifestations. It was concluded that the latex test provides a rapid and simple test in toxoplasmosis that can be used to exclude negative cases as nearly no false negative results were obtained. However, positive cases by latex agglutination should be confirmed and quantitated by another standardized technique.