Gunbey Hediye Pınar, Gunbey Emre, Sayit Aslı Tanrivermis, Aslan Kerim, Unal Asude, Incesu Lutfi
Department of Radiology, Ondokuz Mayıs University, Kurupelit, 55139, Samsun, Turkey.
Department of Otorhinolaryngology, Ondokuz Mayıs University, Samsun, Turkey.
Surg Radiol Anat. 2016 Jul;38(5):551-6. doi: 10.1007/s00276-015-1607-4. Epub 2015 Dec 29.
We hypothesized that the cochlear-carotid interval (CCI), which is defined as the smallest distance along the petrous segment of the internal carotid artery and basal turn of cochlea, may be associated with direct stimulation of hair cells, thereby affecting tinnitus perception. The aim of this study was to investigate the relationships between the CCI, tinnitus perception, and accompanying hearing loss in patients with tinnitus.
The CCI on both sides was measured independently by two observers from the temporal 3D b-FFE MR images of 25 patients with tinnitus and 20 age/gender matched control subjects. The relationships between CCI, tinnitus visual analog scale (VAS), and tinnitus handicap inventory (THI) were investigated.
CCI ranged 0.2-5.6 mm (1.9 ± 1.5) on the right and 0.1-5.4 mm (2.2 ± 1.6) on the left side in the patient group and 0.5-5.4 (1.9 ± 1.4) mm on the right and 0.3-6.7 (2.3 ± 1.7) on the left side in the control group. The differences between the two groups were not statistically significant (p > 0.05). CCI showed a strong negative correlation with THI and VAS scores on both sides. Correlation of audiologic findings with CCI revealed a significant negative correlation with pure tone average of the ipsilateral ear most affectedly at high frequencies.
The strong negative correlation of CCI with tinnitus-related distress and accompanying sensorineural hearing loss predominantly at high frequencies suggests that further studies on patients with tinnitus that focus on this small area may help to improve the knowledge of tinnitus pathophysiology.
我们推测，耳蜗 - 颈动脉间隙（CCI），即沿颈内动脉岩骨段与耳蜗底转之间的最小距离，可能与毛细胞的直接刺激有关，从而影响耳鸣感知。本研究的目的是调查耳鸣患者的CCI、耳鸣感知和伴随的听力损失之间的关系。
由两名观察者独立测量25例耳鸣患者和20例年龄/性别匹配的对照受试者颞部3D b-FFE MR图像上两侧的CCI。研究了CCI、耳鸣视觉模拟量表（VAS）和耳鸣障碍量表（THI）之间的关系。
患者组右侧CCI范围为0.2 - 5.6毫米（1.9±1.5），左侧为0.1 - 5.4毫米（2.2±1.6）；对照组右侧为0.5 - 5.4（1.9±1.4）毫米，左侧为0.3 - 6.7（2.3±1.7）毫米。两组之间的差异无统计学意义（p>0.05）。CCI两侧与THI和VAS评分均呈强负相关。听力检查结果与CCI的相关性显示，与受影响最严重的同侧耳高频纯音平均值呈显著负相关。
CCI与耳鸣相关困扰以及主要在高频出现的伴随感音神经性听力损失之间的强负相关表明，针对这一狭小区域对耳鸣患者进行进一步研究可能有助于增进对耳鸣病理生理学的认识。
