Pasta V, D'Orazi V, Ruggeri L, Toni M F, Urciuoli P, Tellan G
G Chir. 2015 Jul-Aug;36(4):168-71. doi: 10.11138/gchir/2015.36.4.168.
Clinical practice sometimes brings to face with situations quite peculiar, potentially dangerous for the patient's life. In the great majority of cases, pathologies associated with each other (cardiovascular, respiratory, neurological), while in other cases we can treat rare diseases or syndromes. It's considered exceptional the simultaneous presence of "rare" pathologies in a single patient. This exceptionality has been a push to treat a patient as a "unique" asking for help to deeper studies of pharmacogenetics. Our case reports the management of a patient with Ehlers-Danlos syndrome (EDS) and Multiple Chemical Sensitivity (MCS), undergoing a total thyroidectomy. We found several problems, and we tried to find effective solutions for the management of the patient during the whole peri-operative process, from a clinical, pharmacological and also from a surgical point of view.
临床实践有时会面临一些非常特殊的情况，这些情况对患者的生命可能具有潜在危险。在绝大多数情况下，会出现相互关联的病症（心血管、呼吸、神经方面的），而在其他情况下，我们可能会治疗罕见疾病或综合征。在单个患者身上同时出现“罕见”病症被认为是例外情况。这种特殊性促使我们将患者视为一个“独特个体”，并寻求对药物遗传学进行更深入研究的帮助。我们的病例报告了一名患有埃勒斯-当洛综合征（EDS）和多重化学敏感性（MCS）的患者接受全甲状腺切除术的治疗情况。我们发现了几个问题，并试图从临床、药理学以及外科角度，在整个围手术期过程中找到对该患者进行管理的有效解决方案。
