Armstrong April W, Aldredge Lakshi, Yamauchi Paul S
Department of Dermatology, University of Colorado Denver, Aurora, CO, USA
Department of Dermatology, Portland Veterans Affairs Medical Center, Portland, OR, USA.
J Cutan Med Surg. 2016 May;20(3):196-206. doi: 10.1177/1203475415623508. Epub 2015 Dec 28.
Psoriasis is a common inflammatory disease with significant comorbidities, whose management can be challenging given the variety of treatment options. It is critical for nurse practitioners, physician assistants, general practitioners, and dermatology trainees to have useful information about the treatment and monitoring of patients with psoriasis. Although certain aspects of care apply to all patients, each therapeutic agent has its own nuances in terms of assessments, dosing, and monitoring. The most appropriate treatment is based not only on disease severity but also on comorbid conditions and concomitant medications. These practitioners are vital in facilitating patient care by thorough understanding of systemic agents, selection criteria, dosing, and recommended monitoring. This article provides high-yield practical pearls on managing patients with moderate to severe psoriasis. It includes case-based discussions illustrating considerations for special populations, such as pregnant women, children, and patients with comorbidities (eg, human immunodeficiency virus infection, hepatitis C, hepatitis B, and history of malignancy).
银屑病是一种常见的炎症性疾病,常伴有严重的合并症,鉴于治疗选择的多样性,其管理可能具有挑战性。对于执业护士、医师助理、全科医生和皮肤科实习生来说,掌握有关银屑病患者治疗和监测的有用信息至关重要。虽然某些护理方面适用于所有患者,但每种治疗药物在评估、给药和监测方面都有其细微差别。最合适的治疗不仅基于疾病严重程度,还基于合并症和伴随用药情况。这些从业者通过全面了解全身用药、选择标准、给药和推荐的监测方法,对促进患者护理至关重要。本文提供了管理中度至重度银屑病患者的实用要点。它包括基于病例的讨论,阐述了对特殊人群的考虑因素,如孕妇、儿童和合并症患者(如人类免疫缺陷病毒感染、丙型肝炎、乙型肝炎和恶性肿瘤病史)。