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鞘内注射右美托咪定以减轻脊髓麻醉下腹腔镜胆囊切除术的肩部疼痛。

Intrathecal dextmedetomidine to reduce shoulder tip pain in laparoscopic cholecystectomies under spinal anesthesia.

作者信息

Bhatia Tarundeep, Bhatia Jaideep, Attri Joginder Pal, Singh Sukhpreet, Khetarpal Ranjana

机构信息

Department of Anaesthesia, Patiala Surgical Centre, Patiala, India.

Department of Surgical Oncology, Government Medical College, Patiala, India.

出版信息

Anesth Essays Res. 2015 Sep-Dec;9(3):320-5. doi: 10.4103/0259-1162.158010.

DOI:10.4103/0259-1162.158010
PMID:26712967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4683477/
Abstract

BACKGROUND

General anesthesia as a technique for laparoscopic cholecystectomies has disadvantage in terms of the stress response, lack of postoperative analgesia and emesis. Regional anesthesia offers advantages over general anesthesia in terms of cost, postoperative analgesia, intact respiratory control mechanism and early ambulation. Shoulder tip pain remains the main concerns that can be alleviated by adding various adjuvants to local anesthetics.

AIMS AND OBJECTIVES

To study the effect of adding intrathecal dexmedetomidine to bupivacaine to decrease shoulder tip pain, onset and duration of sensory and motor block, hemodynamic changes and side effects if any.

MATERIALS AND METHODS

Totally, 60 patients were divided into two groups of 30 each. Group A received 3 ml of bupivacaine heavy and group B received 5 µg of dexmedetomidine along with 3 ml of bupivacaine diluted to total volume of 3.5 ml in each group.

STATISTICAL ANALYSIS

It was done using Chi-square and Student's t-test.

RESULTS AND CONCLUSIONS

Intrathecal dexmedetomidine provides stable hemodynamics, excellent sedation and analgesia and abolishes shoulder tip pain.

摘要

背景

全身麻醉作为腹腔镜胆囊切除术的一种技术,在应激反应、缺乏术后镇痛和呕吐方面存在劣势。区域麻醉在成本、术后镇痛、完整的呼吸控制机制和早期活动方面比全身麻醉更具优势。肩峰下疼痛仍然是主要问题,可通过在局部麻醉药中添加各种佐剂来缓解。

目的

研究鞘内注射右美托咪定联合布比卡因对减轻肩峰下疼痛、感觉和运动阻滞的起效时间及持续时间、血流动力学变化和副作用(如有)的影响。

材料与方法

总共60例患者被分为两组,每组30例。A组接受3 ml重比重布比卡因,B组接受5 μg右美托咪定加3 ml稀释至总体积3.5 ml的布比卡因。

统计分析

采用卡方检验和学生t检验。

结果与结论

鞘内注射右美托咪定可提供稳定的血流动力学、良好的镇静和镇痛效果,并消除肩峰下疼痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/be682ce111b7/AER-9-320-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/fa30770ffca2/AER-9-320-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/db209eddd43c/AER-9-320-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/1884659b256b/AER-9-320-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/be682ce111b7/AER-9-320-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/fa30770ffca2/AER-9-320-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/db209eddd43c/AER-9-320-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/1884659b256b/AER-9-320-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8472/4683477/be682ce111b7/AER-9-320-g006.jpg

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J Anaesthesiol Clin Pharmacol. 2013 Oct;29(4):496-502. doi: 10.4103/0970-9185.119151.
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Dexmedetomidine as an intrathecal adjuvant for postoperative analgesia.右美托咪定作为鞘内辅助用药用于术后镇痛。
Indian J Anaesth. 2011 Jul;55(4):347-51. doi: 10.4103/0019-5049.84841.
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Evaluation of the effect of intrathecal clonidine to decrease shoulder tip pain in laparoscopy under spinal anaesthesia.
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Retraction: Intrathecal dextmedetomidine to reduce shoulder tip pain in laparoscopic cholecystectomies under spinal anesthesia.撤稿声明:鞘内注射右美托咪定以减轻脊麻下腹腔镜胆囊切除术的肩部疼痛。
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