Utzerath G, Reske D, Gouzoulis-Mayfrank E
Fortschr Neurol Psychiatr. 2015 Dec;83(12):665-75. doi: 10.1055/s-0041-109986. Epub 2015 Dec 29.
This overview presents the current scientific data on intramuscular administration of benperidole, aripiprazole, ziprasidone, and haloperidole and on inhaled loxapine with regard to their efficacy and tolerability as well as their pharmacodynamic and pharmacokinetic properties. In addition, the possible advantages and disadvantages of the different substances are compared when administered to patients who show tension, agitation and aggression.
本综述介绍了关于肌内注射苄哌利多、阿立哌唑、齐拉西酮和氟哌啶醇以及吸入洛沙平在疗效、耐受性、药效学和药代动力学特性方面的现有科学数据。此外,还比较了将不同药物给予表现出紧张、激动和攻击性的患者时可能存在的优缺点。