Singh B, Newton R U, Cormie P, Galvao D A, Cornish B, Reul-Hirche H, Smith C, Nosaka K, Hayes S C
Lymphology. 2015 Jun;48(2):80-92.
The use of compression garments during exercise is recommended for women with breast cancer-related lymphedema, but the evidence behind this clinical recommendation is unclear. The aim of this randomized, cross-over trial was to compare the acute effects of wearing versus not wearing compression during a single bout of moderate-load resistance exercise on lymphedema status and its associated symptoms in women with breast cancer-related lymphedema (BCRL). Twenty-five women with clinically diagnosed, stable unilateral breast cancer-related lymphedema completed two resistance exercise sessions, one with compression and one without, in a randomized order separated by a minimum 6 day wash-out period. The resistance exercise session consisted of six upper-body exercises, with each exercise performed for three sets at a moderate-load (10-12 repetition maximum). Primary outcome was lymphedema, assessed using bioimpedance spectroscopy (L-Dex score). Secondary outcomes were lymphedema as assessed by arm circumferences (percent inter-limb difference and sum-of-circumferences), and symptom severity for pain, heaviness and tightness, measured using visual analogue scales. Measurements were taken pre-, immediately post- and 24 hours post-exercise. There was no difference in lymphedema status (i.e., L-Dex scores) pre- and post-exercise sessions or between the compression and non-compression condition [Mean (SD) for compression pre-, immediately post- and 24 hours post-exercise: 17.7 (21.5), 12.7 (16.2) and 14.1 (16.7), respectively; no compression: 15.3 (18.3), 15.3 (17.8), and 13.4 (16.1), respectively]. Circumference values and symptom severity were stable across time and treatment condition. An acute bout of moderate-load, upper-body resistance exercise performed in the absence of compression does not exacerbate lymphedema in women with BCRL.
对于患有乳腺癌相关淋巴水肿的女性，建议在运动期间使用压力衣，但这一临床建议背后的证据尚不清楚。这项随机交叉试验的目的是比较在单次中度负荷抗阻运动期间穿着与不穿着压力衣对患有乳腺癌相关淋巴水肿（BCRL）的女性的淋巴水肿状况及其相关症状的急性影响。25名临床诊断为稳定的单侧乳腺癌相关淋巴水肿的女性完成了两次抗阻运动训练，一次穿着压力衣，一次不穿，训练顺序随机，中间间隔至少6天的洗脱期。抗阻运动训练包括六项上身运动，每项运动以中度负荷（最大重复次数10 - 12次）进行三组。主要结局是淋巴水肿，采用生物电阻抗光谱法（L - Dex评分）评估。次要结局是通过手臂周长评估的淋巴水肿（肢体间差异百分比和周长总和），以及使用视觉模拟量表测量的疼痛、沉重感和紧绷感的症状严重程度。在运动前、运动后即刻和运动后24小时进行测量。运动前后训练期间或压力衣和无压力衣条件之间的淋巴水肿状况（即L - Dex评分）没有差异[压力衣组运动前、运动后即刻和运动后24小时的平均值（标准差）分别为：17.7（21.5）、12.7（16.2）和14.1（16.7）；无压力衣组分别为：15.3（18.3）、15.3（17.8）和13.4（16.1）]。周长值和症状严重程度在不同时间和治疗条件下保持稳定。在没有压力衣的情况下进行的单次中度负荷上身抗阻运动不会加重BCRL女性的淋巴水肿。
