Xiang Nijuan, Lin Dan, An Guangxu, Sui Haitian, Yang Zhiyong, Li Dan, Zhao Jian, Ma Tao, Wang Yali, Ren Ruiqi, Zhang Xinyan, Ni Daxin, Zhang Yanping, Li Qun
Public Health Emergency Center.
Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Editorial Office of Chinese Journal of Zoonoses, Fujian Provincial Center for Disease Control and Prevention.
Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Aug;36(8):836-41.
To analyze the epidemiological characteristics of Middle East Respiratory Syndrome (MERS) outbreak in the Republic of Korea in 2015 and provide related information for the public health professionals in China.
The incidence data of MERS were collected from the websites of the Korean government, WHO and authoritative media in Korea for this epidemiological analysis.
Between May 20 and July 13, 2015, a total of 186 confirmed MERS cases (1 index case, 29 secondary cases, 125 third generation cases, 25 fourth generation cases and 6 cases without clear generation data), including 36 deaths (case fatality rate: 19%), were reported in Korea. All cases were associated with nosocomial transmission except the index case and two possible family infections. Sixteen hospitals in 11 districts in 5 provinces/municipalities in Korea reported confirmed MERS cases, involving 39 medical professionals or staff. For the confirmed cases and death cases, the median ages were 55 years and 70 years respectively, and the cases and deaths in males accounted for 60% and 67% respectively. Up to 78% of the deaths were with underlying medical conditions. Besides the index case, other 12 patients were reported to cause secondary cases, in which 1 caused 84 infections. One imported MERS case from Korea was confirmed in China on May 29, no secondary cases occurred. The viruses strains isolated from the cases in Korea and the imported case in China show no significant variation compared with the strains isolated in the Middle East.
The epidemiological pattern of the MERS outbreak in Korea was similar to MERS outbreaks occurred in the Middle East.
分析2015年韩国中东呼吸综合征(MERS)疫情的流行病学特征,为我国公共卫生专业人员提供相关信息。
从韩国政府网站、世界卫生组织(WHO)及韩国权威媒体收集MERS发病数据进行本次流行病学分析。
2015年5月20日至7月13日,韩国共报告186例确诊MERS病例(1例首例病例、29例二代病例、125例三代病例、25例四代病例及6例无明确代际数据的病例),其中36例死亡(病死率:19%)。除首例病例及2例可能的家庭感染病例外,所有病例均与医院内传播有关。韩国5个省/直辖市11个区的16家医院报告了确诊的MERS病例,涉及39名医学专业人员或工作人员。确诊病例和死亡病例的中位年龄分别为55岁和70岁,男性病例和死亡分别占60%和67%。高达78%的死亡病例有基础疾病。除首例病例外,另有12例患者导致二代病例,其中1例引发84起感染。5月29日我国确诊1例来自韩国的输入性MERS病例,未发生二代病例。从韩国病例及我国输入病例中分离出的病毒株与中东地区分离出的毒株相比无明显变异。
韩国MERS疫情的流行模式与中东地区发生的MERS疫情相似。