Callen J P
Department of Medicine, University of Louisville School of Medicine, Kentucky.
Med Clin North Am. 1989 Sep;73(5):1247-61.
Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous condition with distinctive clinical characteristics and a frequent association with systemic diseases. Most frequently among the associated disease list are: inflammatory bowel disease, arthritis, and a variety of hematologic disorders. There is no specific treatment of PG; however, the effective treatment of an accompanying systemic disease, local therapy, and/or the use of topical or systemic agents known to be useful in neutrophil disorders, have been beneficial in most patients.
坏疽性脓皮病(PG)是一种罕见的溃疡性皮肤病,具有独特的临床特征,且常与全身性疾病相关。与之相关的疾病中最常见的有:炎症性肠病、关节炎和多种血液系统疾病。目前尚无针对PG的特异性治疗方法;然而,对伴发的全身性疾病进行有效治疗、局部治疗,和/或使用已知对中性粒细胞疾病有效的局部或全身性药物,对大多数患者都有益处。