d'Agay M F, Miclea J M, Clauvel J P, Schaison G, Brocheriou C
Laboratoire d'Anatomie Pathologique, Hôpital Saint-Louis, Paris, France.
Nouv Rev Fr Hematol (1978). 1989;31(2):145-8.
If the histological patterns of Castleman's disease are well defined--hyaline vascular type and plasma cell type--, the clinical spectrum is widely divergent, ranging from localised forms cured by surgical ablation to multicentric idiopathic forms requiring systemic therapy; some cases are associated with an acquired immunodeficiency, such as HIV infection. The pathogeny of the disease is discussed.
如果卡斯特曼病的组织学模式明确——透明血管型和浆细胞型——,那么其临床谱则差异很大,从通过手术切除治愈的局限性形式到需要全身治疗的多中心特发性形式;一些病例与获得性免疫缺陷有关,如HIV感染。本文讨论了该疾病的发病机制。