Labadie Robert F, Noble Jack H, Hedley-Williams Andrea J, Sunderhaus Linsey W, Dawant Benoit M, Gifford René H
*Department of Otolaryngology-Head and Neck Surgery †Department of Electrical Engineering and Computer Science ‡Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, Tennessee, U.S.A.
Otol Neurotol. 2016 Feb;37(2):137-45. doi: 10.1097/MAO.0000000000000926.
To test the use of a novel, image-guided cochlear implant (CI) programming (IGCIP) technique on prelingually deafened, adult CI recipients.
Prospective unblinded study.
Tertiary referral center.
Twenty-six prelingually deafened adult CI recipients with 29 CIs (3 bilateral).
INTERVENTION(S): Temporal-bone CT scans were used as input to a series of semiautomated computer algorithms which estimate the location of electrodes in reference to the modiolus. This information was used to selectively deactivate suboptimally located electrodes, i.e., those for which the distance from the electrode to the modiolus was further than a neighboring electrode to the same site. Patients used the new IGCIP program exclusively for 3-5 weeks.
MAIN OUTCOME MEASURE(S): Minimum Speech Test Battery (MSTB), quality of life (QOL), and spectral modulation detection (SMD).
On average one-third of electrodes were deactivated. At the group level, no significant differences were noted for MSTB measures nor for QOL estimates. Average SMD significantly improved after IGCIP reprogramming, which is consistent with improved spatial selectivity. Using 95% confidence interval data for CNC, AzBio, and BKB-SIN at the individual level, 76 to 90% of subjects demonstrated equivocal or significant improvement. Ultimately 21 of 29 (72.41%) elected to keep the IGCIP map because of perceived benefit often substantiated by improvement on either MSTB, QOL, and/or SMD.
Knowledge of the geometric relationship between CI electrodes and the modiolus appears to be useful in adjusting CI maps in prelingually deafened adults. Long-term improvements may be observed resulting from improved spatial selectivity and spectral resolution.
测试一种新型的、图像引导的人工耳蜗(CI)编程(IGCIP)技术在语前聋成年CI接受者中的应用。
前瞻性非盲研究。
三级转诊中心。
26名语前聋成年CI接受者,共植入29个CI(3例双侧植入)。
颞骨CT扫描被用作一系列半自动计算机算法的输入,这些算法根据蜗轴来估计电极的位置。该信息被用于选择性地停用位置欠佳的电极,即那些电极到蜗轴的距离比同一部位相邻电极更远的电极。患者在3至5周内仅使用新的IGCIP程序。
最小言语测试电池(MSTB)、生活质量(QOL)和频谱调制检测(SMD)。
平均三分之一的电极被停用。在组水平上,MSTB测量值和QOL评估均未发现显著差异。IGCIP重新编程后,平均SMD显著改善,这与空间选择性的提高一致。在个体水平上,使用CNC、AzBio和BKB-SIN的95%置信区间数据,76%至90%的受试者表现出不明确或显著的改善。最终,29名患者中有21名(72.41%)选择保留IGCIP图谱,因为他们认为该图谱带来了益处,这通常由MSTB、QOL和/或SMD的改善所证实。
了解CI电极与蜗轴之间的几何关系似乎有助于调整语前聋成年人的CI图谱。空间选择性和频谱分辨率的提高可能会带来长期改善。