Lin Xing-Yu, Yang Zhi-Guang, Zhang Peng, Liu Yun-Peng, Wang Cheng-Xiang, Shao Guo-Guang
Department of Thoracic Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Oncol Lett. 2015 Nov;10(5):3018-3020. doi: 10.3892/ol.2015.3717. Epub 2015 Sep 17.
Hemophilia is a hereditary disease with impaired blood coagulation due to a genetic deficiency of blood coagulation factors. Hemophilia often causes spontaneous life-threatening bleeding, so patients with hemophilia are often not suitable for any surgery that may cause iatrogenic bleeding and threaten the life of the patient. Therefore, surgery in lung cancer patients with hemophilia is extremely rare. The present study reported the case of a lung cancer patient with hemophilia who presented with a persistent cough. A mass was revealed by computed tomography and the patient underwent a successful thoracoscopic right lower lobectomy. The study discusses the patient's diagnosis and treatment options for hemophilia A and lung cancer, including indications for thoracoscopic lobectomy, pre-operative preparation and post-operative care, and other treatment options are discussed. The literature is also reviewed on this subject.
血友病是一种遗传性疾病，由于凝血因子的基因缺陷导致血液凝固受损。血友病常导致自发性危及生命的出血，因此血友病患者通常不适合任何可能导致医源性出血并危及患者生命的手术。因此，血友病肺癌患者的手术极为罕见。本研究报告了一例患有血友病且持续咳嗽的肺癌患者。计算机断层扫描显示有一个肿块，患者接受了成功的胸腔镜右下叶切除术。该研究讨论了该患者甲型血友病和肺癌的诊断及治疗选择，包括胸腔镜肺叶切除术的适应症、术前准备和术后护理，并探讨了其他治疗选择。还对该主题的文献进行了综述。
