Ma Yangyang, Zheng Jicui, Yang Shaobao, Zhu Haitao, Dong Kuiran, Xiao Xianmin, Chen Lian
Department of Pathology, Children's Hospital of Fudan University Shanghai, China.
Department of Surgery, Children's Hospital of Fudan University Shanghai, China.
Int J Clin Exp Pathol. 2015 Oct 1;8(10):13584-9. eCollection 2015.
Melanotic neuroectodermal tumor of infancy is rare. Only 3 cases have been reported in the soft tissue of the extremities up to date. It has a typically biphasic feature in morphology. Epithelial and melanotic markers are positive in the epitheliod cells and neuron-specific enolase or synaptophysin is positive in the small blue round cells in immunohistochemistry. Radical resection and close follow-up is the treatment strategy in general situation. Here we report one case of MNTI in the upper extremity with review of the literature. This is the first case of MNTI in the forearm.
婴儿黑色素性神经外胚层肿瘤罕见。迄今为止，仅3例报道发生于四肢软组织。其形态学具有典型的双相性特征。免疫组织化学显示，上皮样细胞中上皮和黑色素标记物呈阳性，小蓝圆细胞中神经元特异性烯醇化酶或突触素呈阳性。一般情况下，治疗策略为根治性切除并密切随访。在此，我们报告1例上肢的婴儿黑色素性神经外胚层肿瘤，并复习相关文献。这是首例发生于前臂的婴儿黑色素性神经外胚层肿瘤。
