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使用新型X射线立体成像技术在准静态压力状态下中耳听小骨的三维位移

3D displacement of the middle ear ossicles in the quasi-static pressure regime using new X-ray stereoscopy technique.

作者信息

Salih Wasil H M, Soons Joris A M, Dirckx Joris J J

机构信息

Department of Biomedical Physics, Alneelain University, Algamhouria Avenue, Khartoum, Sudan; Laboratory of Biomedical Physics, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.

Laboratory of Biomedical Physics, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.

出版信息

Hear Res. 2016 Oct;340:60-68. doi: 10.1016/j.heares.2015.12.003. Epub 2015 Dec 23.

DOI:10.1016/j.heares.2015.12.003
PMID:26723101
Abstract

A novel X-ray stereoscopy technique, using greyscale information obtained from moving markers, was used to study the 3D motion in both gerbil and rabbit middle ear ossicles in the quasi-static pressure regime. The motion can be measured without visually exposing the ossicles. The ossicles showed non-linear behaviour as a function of both pressure and frequency. For instance, about 80% of the maximum umbo displacement occurs at a 1 kPa (peak-to-peak) pressure load, while a limited increase of the amplitude is noticed when the pressure goes to 2 kPa. In rabbit the ratio of stapes to umbo motion amplitude was 0.35 for a pressure of 2 kPa (peak-to-peak) at 0.5 Hz. From two stereoscopic projections of the marker paths, 3D motion of the ossicles could be calculated. This motion is demonstrated on high-resolution computer models in order to visualize ossicular chain behaviour.

摘要

一种新颖的X射线立体成像技术,利用从移动标记物获取的灰度信息,用于研究沙鼠和兔中耳听小骨在准静态压力状态下的三维运动。无需目视暴露听小骨即可测量其运动。听小骨表现出与压力和频率相关的非线性行为。例如,最大鼓膜脐位移的约80%出现在1 kPa(峰峰值)的压力负荷下,而当压力升至2 kPa时,振幅的增加有限。在兔中,对于0.5 Hz时2 kPa(峰峰值)的压力,镫骨与鼓膜脐运动振幅之比为0.35。从标记物路径的两个立体投影中,可以计算出听小骨的三维运动。这种运动在高分辨率计算机模型上展示,以便直观呈现听骨链的行为。

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