Pimentel Corrêa Ana Carolina, Cecchin Doglas, de Almeida José Flávio Affonso, Gomes Brenda Paula Figueiredo de Almeida, Zaia Alexandre Augusto, Ferraz Caio Cezar Randi
Department of Restorative Dentistry, Piracicaba Dental School, State University of Campinas, Piracicaba, São Paulo, Brazil.
Department of Restorative Dentistry, Passo Fundo Dental School, University of Passo Fundo, Passo Fundo, Rio Grande do Sul, Brazil.
J Endod. 2016 Feb;42(2):284-8. doi: 10.1016/j.joen.2015.11.010. Epub 2015 Dec 23.
The aim of this study was to evaluate the efficacy of sodium thiosulfate (Na2S2O3) for restoring adhesion to pulp chamber dentin treated with sodium hypochlorite (NaOCl) and EDTA.
Sixty-three crowns of bovine incisors were cut to expose the dentin pulp chamber. The specimens were polished and randomly distributed into 9 groups (n = 7) according to the following protocols used: 0.9% sodium chloride for 30 minutes (negative control), 5.25% NaOCl for 30 minutes, 17% EDTA for 3 minutes, and 5.25% NaOCl for 1 minute (positive control). The other groups, after treatments with NaOCl and EDTA, were immersed in 0.5% or 5% Na2S2O3 for 1, 5, and 10 minutes or just immersed in an inert solution for 10 minutes (0.9% sodium chloride). After drying the specimens, Scotchbond Multi-Purpose (3M ESPE, St Paul, MN) was applied to the pulp chamber dentin followed by Filtek Z250 composite (3M ESPE). Six rectangular slabs were obtained from each specimen, and the dentin/resin interface was tested by using a universal testing machine. The resulting data were submitted to 1-way analysis of variance and the Duncan test (P = .05).
There was a significant decrease in bond strength regarding NaOCl and EDTA (P < .05). When 5% Na2S2O3 was used for 10 minutes, the bond strength was found to be statistically equal to the negative control and higher than the positive control (P < .05).
The use of Na2S2O3 can significantly increase the bond strength of composite resin to NaOCl/EDTA-treated dentin, allowing adhesive restorations to be immediately applied after endodontic treatment.
本研究的目的是评估硫代硫酸钠（Na2S2O3）对恢复经次氯酸钠（NaOCl）和乙二胺四乙酸（EDTA）处理后的髓腔牙本质黏附性的效果。
将63颗牛切牙的牙冠切割以暴露牙本质髓腔。对标本进行抛光，并根据以下使用方案随机分为9组（n = 7）：0.9%氯化钠处理30分钟（阴性对照）、5.25% NaOCl处理30分钟、17% EDTA处理3分钟以及5.25% NaOCl处理1分钟（阳性对照）。其他组在用NaOCl和EDTA处理后，分别浸入0.5%或5%的Na2S2O3中1、5和10分钟，或者仅浸入惰性溶液（0.9%氯化钠）中10分钟。标本干燥后，将Scotchbond多功能粘结剂（3M ESPE，圣保罗，明尼苏达州）应用于髓腔牙本质，随后应用Filtek Z250复合树脂（3M ESPE）。从每个标本中获取六个矩形薄片，并使用万能试验机测试牙本质/树脂界面。所得数据进行单因素方差分析和邓肯检验（P = 0.05）。
与NaOCl和EDTA相比，粘结强度显著降低（P < 0.05）。当使用5% Na2S2O3处理10分钟时，发现粘结强度在统计学上与阴性对照相当且高于阳性对照（P < 0.05）。
使用Na2S2O3可显著提高复合树脂与经NaOCl/EDTA处理的牙本质的粘结强度，使牙髓治疗后能立即进行粘结修复。
