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物理治疗对感染人类嗜T淋巴细胞病毒1型患者神经源性膀胱的治疗效果

Effects of Physiotherapy in the Treatment of Neurogenic Bladder in Patients Infected With Human T-Lymphotropic Virus 1.

作者信息

Andrade Rosana C P, Neto José A, Andrade Luciana, Oliveira Tatiane S, Santos Dislene N, Oliveira Cassius J V, Prado Márcio J, Carvalho Edgar M

机构信息

Physiotherapy Department, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Postgraduate Program in Health Sciences, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil.

Immunology Service, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Postgraduate Program in Health Sciences, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil.

出版信息

Urology. 2016 Mar;89:33-8. doi: 10.1016/j.urology.2015.09.036. Epub 2015 Dec 24.

DOI:10.1016/j.urology.2015.09.036
PMID:26724409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4792685/
Abstract

OBJECTIVE

To evaluate the efficacy of physiotherapy for urinary manifestations in patients with human T-lymphotropic virus 1-associated lower urinary tract dysfunction.

METHODS

Open clinical trial was conducted with 21 patients attending the physiotherapy clinic of the Hospital Universitário, Bahia, Brazil. Combinations of behavioral therapy, perineal exercises, and intravaginal or intra-anal electrical stimulation were used.

RESULTS

The mean age was 54 ± 12 years and 67% were female. After treatment, there was an improvement in symptoms of urinary urgency, frequency, incontinence, nocturia, and in the sensation of incomplete emptying (P < .001). There was also a reduction in the overactive bladder symptom score from 10 ± 4 to 6 ± 3 (P < .001) and an increase in the perineal muscle strength (P <.001). The urodynamic parameters improved, with reduction in the frequency of patients with detrusor hyperactivity from 57.9% to 42.1%, detrusor-sphincter dyssynergia from 31.6% to 5.3%, detrusor hypocontractility from 15.8% to 0%, and detrusor areflexia from 10.5% to 0%, with positive repercussions in the quality of life in all patients.

CONCLUSION

Physiotherapy was effective in cases of human T-lymphotropic virus 1-associated neurogenic bladder, reducing symptoms, increasing perineal muscle strength, and improving urodynamic parameters and quality of life.

摘要

目的

评估物理治疗对人类嗜T淋巴细胞病毒1型相关下尿路功能障碍患者泌尿症状的疗效。

方法

对巴西巴伊亚州大学医院理疗门诊的21例患者进行开放临床试验。采用行为疗法、会阴锻炼以及阴道内或肛门内电刺激相结合的方法。

结果

患者平均年龄为54±12岁,67%为女性。治疗后,尿急、尿频、尿失禁、夜尿症症状以及排尿不尽感均有改善(P<0.001)。膀胱过度活动症症状评分从10±4降至6±3(P<0.001),会阴肌肉力量增加(P<0.001)。尿动力学参数得到改善,逼尿肌过度活动患者的比例从57.9%降至42.1%,逼尿肌-括约肌协同失调从31.6%降至5.3%,逼尿肌收缩力减弱从15.8%降至0%,逼尿肌无反射从10.5%降至0%,对所有患者的生活质量产生了积极影响。

结论

物理治疗对人类嗜T淋巴细胞病毒1型相关神经源性膀胱有效,可减轻症状,增加会阴肌肉力量,改善尿动力学参数和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/601c/4792685/fa4e42a930c3/nihms760726f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/601c/4792685/352cb2169449/nihms760726f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/601c/4792685/fa4e42a930c3/nihms760726f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/601c/4792685/352cb2169449/nihms760726f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/601c/4792685/fa4e42a930c3/nihms760726f2.jpg