Janelia Research Campus, HHMI, 19700 Helix Drive, Ashburn, VA 20147, USA.
Department of Physiology, School of Medicine, Istanbul Medipol University, 34810 Istanbul, Turkey.
Cell Metab. 2016 Feb 9;23(2):234-53. doi: 10.1016/j.cmet.2015.12.002. Epub 2015 Dec 24.
Advances in neuro-technology for mapping, manipulating, and monitoring molecularly defined cell types are rapidly advancing insight into neural circuits that regulate appetite. Here, we review these important tools and their applications in circuits that control food seeking and consumption. Technical capabilities provided by these tools establish a rigorous experimental framework for research into the neurobiology of hunger.
神经技术在图谱绘制、操作和监测分子定义的细胞类型方面的进展正在迅速深入了解调节食欲的神经回路。在这里,我们回顾了这些重要工具及其在控制食物寻求和消费的回路中的应用。这些工具提供的技术能力为饥饿的神经生物学研究建立了严格的实验框架。