Wang Lixia, Yang Shiwei, Cao Jinli, Zhao Shaohua, Wang Wuwei
Key Laboratory of Food Nutrition and Safety, Ministry of Education.
Chem Pharm Bull (Tokyo). 2016;64(1):21-6. doi: 10.1248/cpb.c15-00571.
The coacervation between gelatin and sodium alginate for ginger volatile oil (GVO) microencapsulation as functions of mass ratio, pH and concentration of wall material and core material load was evaluated. The microencapsulation was characterized by scanning electron microscopy (SEM), Fourier transform infrared (FT-IR), and thermal gravimetric analysis (TGA). SEM and FT-IR studies indicated the formation of polyelectrolyte complexation between gelatin and sodium alginate and successful encapsulation of GVO into the microcapsules. Thermal property study showed that the crosslinked microparticles exhibited higher thermal stability than the neat GVO, gelatin, and sodium alginate. The stability of microencapsulation of GVO in a simulated gastric and an intestinal situation in vitro was also studied. The stability results indicated that the release of GVO from microcapsules was much higher in simulated intestinal fluid, compared with that in simulated-gastric fluid.
评估了明胶与海藻酸钠之间的凝聚作用对姜挥发油(GVO)微胶囊化的影响,考察了质量比、pH值、壁材浓度和芯材负载量等因素。通过扫描电子显微镜(SEM)、傅里叶变换红外光谱(FT-IR)和热重分析(TGA)对微胶囊进行了表征。SEM和FT-IR研究表明明胶与海藻酸钠之间形成了聚电解质络合物,并且GVO成功包封在微胶囊中。热性能研究表明,交联微颗粒比纯GVO、明胶和海藻酸钠具有更高的热稳定性。还研究了GVO微胶囊在体外模拟胃液和肠液中的稳定性。稳定性结果表明,与模拟胃液相比,GVO从微胶囊在模拟肠液中的释放量要高得多。