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JAK2V617F and CALR double mutations are more frequently encountered in patients with low JAK2V617F allelic burdens.

作者信息

Mansier Olivier, Migeon Marina, Etienne Gabriel, Bidet Audrey, Lippert Eric

机构信息

a Laboratoire d'Hématologie , CHU de Bordeaux ;

b Hématopoïèse leucémique et cibles thérapeutiques, INSERM U1035, Université de Bordeaux ;

出版信息

Leuk Lymphoma. 2016 Aug;57(8):1949-51. doi: 10.3109/10428194.2015.1116122. Epub 2016 Jan 4.

DOI:10.3109/10428194.2015.1116122
PMID:26727159
Abstract
摘要

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JAK2V617F and CALR double mutations are more frequently encountered in patients with low JAK2V617F allelic burdens.JAK2V617F和CALR双突变在JAK2V617F等位基因负担较低的患者中更常见。
Leuk Lymphoma. 2016 Aug;57(8):1949-51. doi: 10.3109/10428194.2015.1116122. Epub 2016 Jan 4.
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Clinical features of Japanese polycythemia vera and essential thrombocythemia patients harboring CALR, JAK2V617F, JAK2Ex12del, and MPLW515L/K mutations.携带CALR、JAK2V617F、JAK2Ex12del和MPLW515L/K突变的日本真性红细胞增多症和原发性血小板增多症患者的临床特征。
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Frequencies, Laboratory Features, and Granulocyte Activation in Chinese Patients with CALR-Mutated Myeloproliferative Neoplasms.中国CALR突变型骨髓增殖性肿瘤患者的频率、实验室特征及粒细胞活化
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A meta-analysis comparing clinical characteristics and outcomes in CALR-mutated and JAK2V617F essential thrombocythaemia.一项比较CALR突变型和JAK2V617F突变型原发性血小板增多症临床特征及预后的荟萃分析。
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JAK2V617F mutation is associated with special alleles in essential thrombocythemia.JAK2V617F 突变与特发性血小板增多症中的特殊等位基因有关。
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Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera.原发性血小板增多症和真性红细胞增多症中的驱动突变（JAK2V617F、MPLW515L/K或CALR）、五聚体蛋白3和C反应蛋白。
J Hematol Oncol. 2017 Feb 22;10(1):54. doi: 10.1186/s13045-017-0425-z.
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Occurrence of JAK2V617F mutation in previously triple negative essential thrombocythemia.既往三阴性原发性血小板增多症中JAK2V617F突变的发生情况
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The impact of JAK2V617F mutation on different types of thrombosis risk in patients with essential thrombocythemia: a meta-analysis.JAK2V617F突变对原发性血小板增多症患者不同类型血栓形成风险的影响：一项荟萃分析。
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[Correlations of jak2v617f mutation with clinical and laboratory findings in primary thrombocythemia patients].
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Impact of JAK2V617F Mutation Burden on Disease Phenotype in Chinese Patients with JAK2V617F-positive Polycythemia Vera (PV) and Essential thrombocythemia (ET).JAK2V617F突变负荷对中国JAK2V617F阳性真性红细胞增多症（PV）和原发性血小板增多症（ET）患者疾病表型的影响
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Ann Hematol. 2025 Mar;104(3):1587-1596. doi: 10.1007/s00277-025-06326-w. Epub 2025 Apr 1.
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Imatinib Treatment of Chronic Myeloid Leukemia Reveals a Preexisting CALR-mutated Essential Thrombocythemia.伊马替尼治疗慢性髓性白血病揭示了一种先前存在的CALR突变型原发性血小板增多症。
Hemasphere. 2018 Feb 5;2(1):e29. doi: 10.1097/HS9.0000000000000029. eCollection 2018 Jan-Feb.
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The Role of New Technologies in Myeloproliferative Neoplasms.
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